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Radiotherapy, Intensity-Modulated

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A hybrid optimization strategy for deliverable intensity-modulated radiotherapy plan generation using deep learning-based dose prediction.

Medical physics
PURPOSE: To propose a clinically feasible automatic planning solution for external beam intensity-modulated radiotherapy, including dose prediction via a deep learning and voxel-based optimization strategy.

Dosimetric impact of deep learning-based CT auto-segmentation on radiation therapy treatment planning for prostate cancer.

Radiation oncology (London, England)
BACKGROUND: The evaluation of automatic segmentation algorithms is commonly performed using geometric metrics. An analysis based on dosimetric parameters might be more relevant in clinical practice but is often lacking in the literature. The aim of t...

Site-agnostic 3D dose distribution prediction with deep learning neural networks.

Medical physics
PURPOSE: Typically, the current dose prediction models are limited to small amounts of data and require retraining for a specific site, often leading to suboptimal performance. We propose a site-agnostic, three-dimensional dose distribution predictio...

Development of a deep learning-based patient-specific target contour prediction model for markerless tumor positioning.

Medical physics
PURPOSE: For pancreatic cancer patients, image guided radiation therapy and real-time tumor tracking (RTTT) techniques can deliver radiation to the target accurately. Currently, for the radiation therapy machine with kV X-ray imaging systems, interna...

Deep learning-based 3Ddose reconstruction with an electronic portal imaging device for magnetic resonance-linear accelerators: a proof of concept study.

Physics in medicine and biology
To develop a novel deep learning-based 3Ddose reconstruction framework with an electronic portal imaging device (EPID) for magnetic resonance-linear accelerators (MR-LINACs).The proposed method directly back-projected 2D portal dose into 3D patient c...

A comparative study of auto-contouring softwares in delineation of organs at risk in lung cancer and rectal cancer.

Scientific reports
Radiotherapy requires the target area and the organs at risk to be contoured on the CT image of the patient. During the process of organs-at-Risk (OAR) of the chest and abdomen, the doctor needs to contour at each CT image. The delineations of large ...

A deep-learning method for generating synthetic kV-CT and improving tumor segmentation for helical tomotherapy of nasopharyngeal carcinoma.

Physics in medicine and biology
Megavoltage computed tomography (MV-CT) is used for setup verification and adaptive radiotherapy in tomotherapy. However, its low contrast and high noise lead to poor image quality. This study aimed to develop a deep-learning-based method to generate...

Evaluation of deep learning-based autosegmentation in breast cancer radiotherapy.

Radiation oncology (London, England)
PURPOSE: To study the performance of a proposed deep learning-based autocontouring system in delineating organs at risk (OARs) in breast radiotherapy with a group of experts.

Deep learning-augmented radioluminescence imaging for radiotherapy dose verification.

Medical physics
PURPOSE: We developed a novel dose verification method using a camera-based radioluminescence imaging system (CRIS) combined with a deep learning-based signal processing technique.