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Receptors, Antigen, T-Cell, alpha-beta

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Feature selection using a one dimensional naïve Bayes' classifier increases the accuracy of support vector machine classification of CDR3 repertoires.

Bioinformatics (Oxford, England) 28073756
MOTIVATION: Somatic DNA recombination, the hallmark of vertebrate adaptive immunity, has the potential to generate a vast diversity of antigen receptor sequences. How this diversity captures antigen specificity remains incompletely understood. In thi...
Amino Acids Animals Bayes Theorem CD4-Positive T-Lymphocytes Complementarity Determining Regions Databases, Genetic Humans Mice, Inbred C57BL Receptors, Antigen, T-Cell, alpha-beta Support Vector Machine
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Single T Cell Sequencing Demonstrates the Functional Role of TCR Pairing in Cell Lineage and Antigen Specificity.

Frontiers in immunology 31417541
Although structural studies of individual T cell receptors (TCRs) have revealed important roles for both the α and β chain in directing MHC and antigen recognition, repertoire-level immunogenomic analyses have historically examined the β chain alone....
Antigens CD4-Positive T-Lymphocytes CD8-Positive T-Lymphocytes Complementarity Determining Regions Humans Machine Learning Receptors, Antigen, T-Cell, alpha-beta Sequence Analysis, Protein
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