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Computational design of clinical trials using a combination of simulation and the genetic algorithm.

CPT: pharmacometrics & systems pharmacology
Artificial intelligence (AI) has come to be used in various technological fields in recent years. However, there have been no reports of AI-designed clinical trials. In this study, we tried to develop study designs by a genetic algorithm (GA), which ...

Bayesian Statistics for Medical Devices: Progress Since 2010.

Therapeutic innovation & regulatory science
The use of Bayesian statistics to support regulatory evaluation of medical devices began in the late 1990s. We review the literature, focusing on recent developments of Bayesian methods, including hierarchical modeling of studies and subgroups, borro...

Formulation and Characterization of Buccal Films Containing Valsartan with Additional Support from Image Analysis.

AAPS PharmSciTech
The present study was aimed to the development and characterization of valsartan-containing buccal films with an introduction to a novel technique of image analysis. Visual inspection of the film provided a wealth of information that was difficult to...

Effect of multimodal comprehensive communication skills training with video analysis by artificial intelligence for physicians on acute geriatric care: a mixed-methods study.

BMJ open
OBJECTIVES: To quantitatively analyse by artificial intelligence (AI) the communication skills of physicians in an acute care hospital for geriatric care following a multimodal comprehensive care communication skills training programme and to qualita...

Efficient Selection of Gaussian Kernel SVM Parameters for Imbalanced Data.

Genes
For medical data mining, the development of a class prediction model has been widely used to deal with various kinds of data classification problems. Classification models especially for high-dimensional gene expression datasets have attracted many r...

Determinants of implementing artificial intelligence-based clinical decision support tools in healthcare: a scoping review protocol.

BMJ open
INTRODUCTION: Artificial intelligence (AI), the simulation of human intelligence processes by machines, is being increasingly leveraged to facilitate clinical decision-making. AI-based clinical decision support (CDS) tools can improve the quality of ...

Evaluation of a decided sample size in machine learning applications.

BMC bioinformatics
BACKGROUND: An appropriate sample size is essential for obtaining a precise and reliable outcome of a study. In machine learning (ML), studies with inadequate samples suffer from overfitting of data and have a lower probability of producing true effe...

Prediction models for the impact of the COVID-19 pandemic on research activities of Japanese nursing researchers using deep learning.

Japan journal of nursing science : JJNS
AIM: This study aimed to construct and evaluate prediction models using deep learning to explore the impact of attributes and lifestyle factors on research activities of nursing researchers during the COVID-19 pandemic.

Deception detection with machine learning: A systematic review and statistical analysis.

PloS one
Several studies applying Machine Learning to deception detection have been published in the last decade. A rich and complex set of settings, approaches, theories, and results is now available. Therefore, one may find it difficult to identify trends, ...

Interpretable machine learning for dementia: A systematic review.

Alzheimer's & dementia : the journal of the Alzheimer's Association
INTRODUCTION: Machine learning research into automated dementia diagnosis is becoming increasingly popular but so far has had limited clinical impact. A key challenge is building robust and generalizable models that generate decisions that can be rel...