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RNA-Binding Proteins

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Recent Advances in Machine Learning Based Prediction of RNA-protein Interactions.

Protein and peptide letters Jan 1, 2019
The interactions between RNAs and proteins play critical roles in many biological processes. Therefore, characterizing these interactions becomes critical for mechanistic, biomedical, and clinical studies. Many experimental methods can be used to det...
Machine Learning Algorithms Computational Biology RNA-Binding Proteins Molecular Dynamics Simulation RNA Hydrophobic and Hydrophilic Interactions Nucleic Acid Conformation
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A deep neural network approach for learning intrinsic protein-RNA binding preferences.

Bioinformatics (Oxford, England) Sep 1, 2018
MOTIVATION: The complexes formed by binding of proteins to RNAs play key roles in many biological processes, such as splicing, gene expression regulation, translation and viral replication. Understanding protein-RNA binding may thus provide important...
Neural Networks, Computer Software Deep Learning RNA-Binding Proteins RNA
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A deep boosting based approach for capturing the sequence binding preferences of RNA-binding proteins from high-throughput CLIP-seq data.

Nucleic acids research Aug 21, 2017
Characterizing the binding behaviors of RNA-binding proteins (RBPs) is important for understanding their functional roles in gene expression regulation. However, current high-throughput experimental methods for identifying RBP targets, such as CLIP-s...
Humans Machine Learning Algorithms Reproducibility of Results Protein Binding Computational Biology RNA-Binding Proteins Mutation Internet High-Throughput Nucleotide Sequencing Gene Expression Regulation Base Sequence Binding Sites Nucleotide Motifs Binding, Competitive 3' Untranslated Regions
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RBPPred: predicting RNA-binding proteins from sequence using SVM.

Bioinformatics (Oxford, England) Mar 15, 2017
MOTIVATION: Detection of RNA-binding proteins (RBPs) is essential since the RNA-binding proteins play critical roles in post-transcriptional regulation and have diverse roles in various biological processes. Moreover, identifying RBPs by computationa...
Humans Software Computational Biology RNA-Binding Proteins Support Vector Machine RNA
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