OBJECTIVE: Despite the multitude of longitudinal neuroimaging studies that have been published, a basic question on the progressive brain loss in schizophrenia remains unaddressed: Does it reflect accelerated aging of the brain, or is it caused by a ...
Recent years have shown the critical importance of inter-regional neural network connectivity in supporting healthy brain function. Such connectivity is measurable using neuroimaging techniques such as MEG, however the richness of the electrophysiolo...
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
Oct 9, 2015
OBJECTIVES: This study investigates whether abnormal neural oscillations, which have been shown to precede the onset of frank psychosis, could be used towards the individualised prediction of psychosis in clinical high-risk patients.
Functional connectivity (FC) patterns obtained from resting-state functional magnetic resonance imaging data are commonly employed to study neuropsychiatric conditions by using pattern classifiers such as the support vector machine (SVM). Meanwhile, ...
Neural networks : the official journal of the International Neural Network Society
Apr 23, 2015
Resting state functional Magnetic Resonance Imaging (rs-fMRI) is increasingly used for the identification of image biomarkers of brain diseases or psychiatric conditions such as schizophrenia. This paper deals with the application of ensembles of Ext...
Schizophrenia stands for a long-lasting state of mental uncertainty that may bring to an end the relation among behavior, thought, and emotion; that is, it may lead to unreliable perception, not suitable actions and feelings, and a sense of mental fr...
International journal of neural systems
Jan 19, 2015
Auditory hallucinations (AH) are a symptom that is most often associated with schizophrenia, but patients with other neuropsychiatric conditions, and even a small percentage of healthy individuals, may also experience AH. Elucidating the neural mecha...
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Aug 27, 2014
OBJECTIVE: To develop a machine learning (ML) methodology based on features extracted from odd-ball auditory evoked potentials to identify neurophysiologic changes induced by Clozapine (CLZ) treatment in responding schizophrenic (SCZ) subjects. This ...
European child & adolescent psychiatry
Aug 11, 2014
Identifying early-onset schizophrenia spectrum disorders (SSD) at a very early stage remains challenging. To assess the diagnostic predictive value of multiple types of data at the emergence of early-onset first-episode psychosis (FEP), various suppo...
BACKGROUND: Cognitive deficits are a central feature of schizophrenia for which there are not any established pharmacological treatments. Antipsychotics are the mainstay of schizophrenia therapy but the effects of these and other psychotropic medicat...
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