AIMC Topic: Sialic Acid Binding Ig-like Lectin 2

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Recent advances in monoclonal antibody development for treatment of B-cell acute lymphoblastic leukemia.

Leukemia & lymphoma Jun 2, 2025
Monoclonal antibody (mAb)-based therapies targeting CD19, CD20, and CD22 have revolutionized B-ALL treatment, offering precision and reduced systemic toxicity by engaging immune mechanisms to eliminate leukemic cells. This review synthesizes literatu...
Humans Drug Development Antineoplastic Agents, Immunological Antibodies, Monoclonal Sialic Acid Binding Ig-like Lectin 2 Antibodies, Bispecific Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
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Integrated machine learning pipeline for aberrant biomarker enrichment (i-mAB): characterizing clusters of differentiation within a compendium of systemic lupus erythematosus patients.

AMIA ... Annual Symposium proceedings. AMIA Symposium Dec 5, 2018
Clusters of differentiation () are cell surface biomarkers that denote key biological differences between cell types and disease state. CD-targeting therapeutic monoclonal antibodies () afford rich trans-disease repositioning opportunities. Within a ...
Humans Machine Learning Biomarkers Female Aged Young Adult Adult Male Middle Aged Case-Control Studies Adolescent Child Cell Differentiation Lupus Erythematosus, Systemic Reference Values Antigens, CD20 Cell Adhesion Molecules Ki-1 Antigen Sialic Acid Binding Ig-like Lectin 2
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