International journal of molecular sciences
Apr 22, 2019
Anticancer peptides (ACPs) are promising therapeutic agents for targeting and killing cancer cells. The accurate prediction of ACPs from given peptide sequences remains as an open problem in the field of immunoinformatics. Recently, machine learning ...
Computer methods and programs in biomedicine
Apr 17, 2019
BACKGROUND AND OBJECTIVES: With rapid development of telehealth system and cloud platform, traditional 12-ECG signals with high resolution generate heavy burdens in data storage and transmission. This problem is increasingly addressed with various EC...
Predicting protein structure from sequence is a central challenge of biochemistry. Co-evolution methods show promise, but an explicit sequence-to-structure map remains elusive. Advances in deep learning that replace complex, human-designed pipelines ...
Pathological estimation of tumor necrosis after chemotherapy is essential for patients with osteosarcoma. This study reports the first fully automated tool to assess viable and necrotic tumor in osteosarcoma, employing advances in histopathology digi...
Recent developments in high-resolution mass spectrometry (HRMS) technology enabled ultrasensitive detection of proteins, peptides, and metabolites in limited amounts of samples, even single cells. However, extraction of trace-abundance signals from c...
This work reports a multilead interval measurement algorithm for a high-resolution digital electrocardiograph. The software enables off-line ECG processing including detection as well as an accurate multilead interval detection algorithm using sup...
Polyadenylation signals (PAS) are found in most protein-coding and some non-coding genes in eukaryotes. Their accurate recognition improves understanding gene regulation mechanisms and recognition of the 3'-end of transcribed gene regions where prema...
The interpretation of pulmonary function tests (PFTs) to diagnose respiratory diseases is built on expert opinion that relies on the recognition of patterns and the clinical context for detection of specific diseases. In this study, we aimed to explo...
We have been developing a human mimetic musculoskeletal humanoid called Kenshiro, whose design concept is to thoroughly pursue an unprecedented anatomical fidelity to the human musculoskeletal structure. We believe that research on human mimetic musc...
BACKGROUND: Although software tools abound for the comparison, analysis, identification, and classification of genomic sequences, taxonomic classification remains challenging due to the magnitude of the datasets and the intrinsic problems associated ...
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