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Synthetic Biology

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[Design and practice of integrating artificial intelligence into the teaching of "Synthetic Biology" under the background of discipline crossing].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
In recent years, artificial intelligence has been employed to empower synthetic biology, demonstrating great potential in the simulation and prediction of protein structures as well as the design and optimization of regulatory elements and metabolic ...

Engineering Sequestration-Based Biomolecular Classifiers with Shared Resources.

ACS synthetic biology
Constructing molecular classifiers that enable cells to recognize linear and nonlinear input patterns would expand the biocomputational capabilities of engineered cells, thereby unlocking their potential in diagnostics and therapeutic applications. W...

Neonatal bioethics, AI, and genomics.

Early human development
Artificial intelligence (AI) and synthetic biology will transform civilization. The only question is how. In this paper, I explore some recent developments in medical AI, genomics, and synthetic biology. I speculate about the implications of these te...

Synthetic biology and artificial intelligence in crop improvement.

Plant communications
Synthetic biology plays a pivotal role in improving crop traits and increasing bioproduction through the use of engineering principles that purposefully modify plants through "design, build, test, and learn" cycles, ultimately resulting in improved b...

Bringing neural networks to life.

Science (New York, N.Y.)
A synthetic protein-based winner-take-all neural network controls cell fate decisions.

A synthetic protein-level neural network in mammalian cells.

Science (New York, N.Y.)
Artificial neural networks provide a powerful paradigm for nonbiological information processing. To understand whether similar principles could enable computation within living cells, we combined de novo-designed protein heterodimers and engineered v...

Machine learning for synthetic gene circuit engineering.

Current opinion in biotechnology
Synthetic biology leverages engineering principles to program biology with new functions for applications in medicine, energy, food, and the environment. A central aspect of synthetic biology is the creation of synthetic gene circuits - engineered bi...

AI-driven automated discovery tools reveal diverse behavioral competencies of biological networks.

eLife
Many applications in biomedicine and synthetic bioengineering rely on understanding, mapping, predicting, and controlling the complex behavior of chemical and genetic networks. The emerging field of diverse intelligence investigates the problem-solvi...

BioTRY: A Comprehensive Knowledge Base for Titer, Rate, and Yield of Biosynthesis.

ACS synthetic biology
Synthetic biology is rapidly evolving into a data-intensive science that increasingly relies on massive data sets; one of its applications is the evaluation of the economic viability of fermentation processes. However, the key economic indicators, na...

Engineering the future of medicine: Natural products, synthetic biology and artificial intelligence for next-generation therapeutics.

Clinical and translational medicine
The eXchange Unit between Thiolation domains approach and artificial intelligence (AI)-driven tools like Synthetic Intelligence are transforming nonribosomal peptide synthetase and polyketide synthase engineering, enabling the creation of novel bioac...