Pharmaceutical development and technology
Apr 24, 2014
Novel granulated pellets technique was adopted to prepare granulated pellet-containing tablets (GPCT). GPCT and traditional pellet-containing tablets (PCT) were prepared according to 29 formulations devised by the Design Expert 7.0, with doxycycline ...
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Aug 1, 2025
The disintegration time for solid dosage oral formulations is directly influenced by diverse factors such as molecular properties, physical characteristics, excipient compositions, and formulation-specific attributes. This research addresses the chal...
A comprehensive characterization strategy for the intelligent analysis of multiple chemical components in Yangxinshi Tablet (YXST) was established. The strategy developed the deep learning-assisted mass defect filtering intelligent classification, pr...
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Jul 1, 2025
Nowadays the increased need for pharmaceutics requires fast, cheap and reliable quality control systems to investigate the final product's quality. The generally used methods like high-pressure liquid chromatography (HPLC) and other coupled technique...
International journal of pharmaceutics
Jun 10, 2025
This study presents a real-time system that integrates deep learning and machine vision for defect detection and coating thickness measurement of irregularly shaped film-coated tablets. To overcome the accuracy and speed limitations of the traditiona...
International journal of pharmaceutics
Jun 10, 2025
Sticking can significantly affect drug product quality, manufacturing efficiency, and therapeutic efficacy in pharmaceutical tablet manufacturing. This study presents a novel integrated model with a convolutional neural network (CNN) and gray-level c...
Luminescence : the journal of biological and chemical luminescence
May 1, 2025
In this study, we present a direct, sensitive, and green spectrofluorimetric approach for simultaneous measurement of bisoprolol fumarate (BSL) and amlodipine besylate (AMD) in their tablets and plasma. This approach measures the synchronized fluores...
BACKGROUND: Tablet formulation could be revolutionized by the integration of modern technology and established pharmaceutical sciences. The pharmaceutical sector can develop tablet formulations that are not only more efficient and stable but also pat...
INTRODUCTION: Oral domperidone is a prokinetic drug that enhances gastric emptying, which has a positive effect in decreasing gastric residual volume (GRV), subsequently decreasing the risk of pulmonary aspiration. This study aimed to assess the effe...
The purpose of this study was to develop a model for predicting tablet properties after an accelerated test and to determine whether molecular descriptors affect tablet properties. Tablets were prepared using 81 types of active pharmaceutical ingredi...
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