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Telomere Homeostasis

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Digital telomere measurement by long-read sequencing distinguishes healthy aging from disease.

Nature communications
Telomere length is an important biomarker of organismal aging and cellular replicative potential, but existing measurement methods are limited in resolution and accuracy. Here, we deploy digital telomere measurement (DTM) by nanopore sequencing to un...

Cell-free plasma telomere length correlated with the risk of cardiovascular events using machine learning classifiers.

Scientific reports
This retrospective study explored the association between circulating cell-free plasma telomere length (cf-TL) and coronary artery disease (CAD) and heart failure (HF). Data from 518 participants were collected, including clinical and laboratory data...