Advances in experimental medicine and biology
Jan 1, 2020
The skin is the largest organ of our body. Skin disease abnormalities which occur within the skin layers are difficult to examine visually and often require biopsies to make a confirmation on a suspected condition. Such invasive methods are not well-...
PURPOSE: In diabetic patients presenting with macular edema (ME) shortly after cataract surgery, identifying the underlying pathology can be challenging and influence management. Our aim was to develop a simple clinical classifier able to confirm a d...
We developed machine learning methods to identify fibrolipidic and fibrocalcific A-lines in intravascular optical coherence tomography (IVOCT) images using a comprehensive set of handcrafted features. We incorporated features developed in previous st...
Automatic and accurate segmentation of intravascular optical coherence tomography imagery is of great importance in computer-aided diagnosis and in treatment of cardiovascular diseases. However, this task has not been well addressed for two reasons. ...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2019
Optical Coherence Tomography (OCT) technology enabled the experts to analyze coronary lesions from high-resolution intravascular images. Studies have shown the relationship between bifurcation regions and a higher occurrence of wall thickening and le...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2019
The objective of this study was to build deep learning models with optical coherence tomography (OCT) images to classify normal and age related macular degeneration (AMD), AMD with fluid, and AMD without any fluid. In this study, 185 normal OCT image...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2019
We describe and assess convolutional neural network (CNN) models for detection of glaucoma based upon optical coherence tomography (OCT) retinal nerve fiber layer (RNFL) probability maps. CNNs pretrained on natural images performed comparably to CNNs...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2019
Intra-retinal cysts (IRCs) are significant in detecting several ocular and retinal pathologies. Segmentation and quantification of IRCs from optical coherence tomography (OCT) scans is a challenging task due to present of speckle noise and scan inten...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2019
Development of an automated sub-retinal fluid segmentation technique from optical coherence tomography (OCT) scans is faced with challenges such as noise and motion artifacts present in OCT images, variation in size, shape and location of fluid pocke...
Investigative ophthalmology & visual science
Jun 3, 2019
PURPOSE: To use supervised machine learning to predict visual function from retinal structure in retinitis pigmentosa (RP) and apply these estimates to CEP290- and NPHP5-associated Leber congenital amaurosis (LCA) to determine the potential for funct...