Optical projection tomography (OPT) is a 3D mesoscopic imaging modality that can utilize absorption or fluorescence contrast. 3D images can be rapidly reconstructed from tomographic data sets sampled with sufficient numbers of projection angles using...
Diffuse optical tomography (DOT) has been investigated as an alternative imaging modality for breast cancer detection thanks to its excellent contrast to hemoglobin oxidization level. However, due to the complicated non-linear photon scattering physi...
Presence of exudates on a retina is an early sign of diabetic retinopathy, and automatic detection of these can improve the diagnosis of the disease. Convolutional Neural Networks (CNNs) have been used for automatic exudate detection, but with poor p...
The imaging performance of fluorescence molecular tomography (FMT) improves when information from the underlying anatomy is incorporated into the inversion scheme, in the form of priors. The requirement for incorporation of priors has recently driven...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
Fluorescence molecular tomography (FMT) is a powerful imaging technique for 3D reconstruction of internal fluorescent sources. However, its spatial resolution is limited by a simplified forward model and an ill-posed inverse problem. To address this,...
Cerebral cortex (New York, N.Y. : 1991)
Jun 4, 2024
Neocortex is a complex structure with different cortical sublayers and regions. However, the precise positioning of cortical regions can be challenging due to the absence of distinct landmarks without special preparation. To address this challenge, w...
Advances in experimental medicine and biology
Jan 1, 2023
Time is one of the most critical factors in preventing brain lesions due to hypoxic ischemia in preterm infants. Since early detection of low oxygenation is vital and the time window for therapy is narrow, near-infrared optical tomography (NIROT) mus...
SIGNIFICANCE: "Difference imaging," which reconstructs target optical properties using measurements with and without target information, is often used in diffuse optical tomography (DOT) in vivo imaging. However, taking additional reference measureme...
SIGNIFICANCE: Deep learning (DL) models are being increasingly developed to map sensor data to the image domain directly. However, DL methodologies are data-driven and require large and diverse data sets to provide robust and accurate image formation...
SIGNIFICANCE: Biomedical optics system design, image formation, and image analysis have primarily been guided by classical physical modeling and signal processing methodologies. Recently, however, deep learning (DL) has become a major paradigm in com...
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