BACKGROUND: Building visual encoding models to accurately predict visual responses is a central challenge for current vision-based brain-machine interface techniques. To achieve high prediction accuracy on neural signals, visual encoding models shoul...
Goal-driven and feedforward-only convolutional neural networks (CNN) have been shown to be able to predict and decode cortical responses to natural images or videos. Here, we explored an alternative deep neural network, variational auto-encoder (VAE)...
The Journal of neuroscience : the official journal of the Society for Neuroscience
Aug 14, 2019
Recent studies showed agreement between how the human brain and neural networks represent objects, suggesting that we might start to understand the underlying computations. However, we know that the human brain is prone to biases at many perceptual a...
Deep convolutional neural networks (CNNs) have certain structural, mechanistic, representational, and functional parallels with primate visual cortex and also many differences. However, perhaps some of the differences can be reconciled. This study de...
Patch clamping is the gold standard measurement technique for cell-type characterization in vivo, but it has low throughput, is difficult to scale, and requires highly skilled operation. We developed an autonomous robot that can acquire multiple cons...
Particular deep artificial neural networks (ANNs) are today's most accurate models of the primate brain's ventral visual stream. Using an ANN-driven image synthesis method, we found that luminous power patterns (i.e., images) can be applied to primat...
Proceedings of the National Academy of Sciences of the United States of America
Apr 23, 2019
Calcium imaging records large-scale neuronal activity with cellular resolution in vivo. Automated, fast, and reliable active neuron segmentation is a critical step in the analysis workflow of utilizing neuronal signals in real-time behavioral studies...
Primary visual cortex (V1) is the first stage of cortical image processing, and major effort in systems neuroscience is devoted to understanding how it encodes information about visual stimuli. Within V1, many neurons respond selectively to edges of ...
Despite great efforts over several decades, our best models of primary visual cortex (V1) still predict spiking activity quite poorly when probed with natural stimuli, highlighting our limited understanding of the nonlinear computations in V1. Recent...
A comprehensive understanding of the stimulus-response properties of individual neurons is necessary to crack the neural code of sensory cortices. However, a barrier to achieving this goal is the difficulty of analysing the nonlinearity of neuronal r...