BACKGROUND: Current clinical guidelines recommend gene expression profiling to guide treatment in early-stage breast cancer. PreciseBreast (PDxBR) is a digital prognostic tool that integrates artificial intelligence (AI)-derived features from hematox... read more
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Aug 20, 2025
Single-cell cis-regulatory relationships (CRRs) are essential for deciphering transcriptional regulation and understanding the pathogenic mechanisms of disease-associated non-coding variants. Existing computational methods struggle to accurately pred... read more
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Aug 20, 2025
The discovery of effective therapeutics remains a complex, costly, and time-consuming endeavor, characterized by high failure rates and significant resource investments. A central bottleneck in early-stage drug discovery is identifying suitable hit c... read more
Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing
Aug 20, 2025
BACKGROUND: Artificial Intelligence is revolutionizing healthcare by addressing complex challenges and enhancing patient care. AI technologies, such as machine learning, natural language processing, and predictive analytics, offer significant potenti... read more
Inclusive design has evolved as a design approach and a research topic in the last three decades. Despite its evolution, there are new frontiers to consider in the context of two phenomena: global ageing populations and the digital transition of serv... read more
Small (Weinheim an der Bergstrasse, Germany)
Aug 20, 2025
Chronic and complex wounds pose a major clinical challenge due to the intricate skin architecture and the multifactorial nature of healing. Conventional wound care often fails to restore native skin function and structure. Advances in 3D and 4D biopr... read more
International journal of retina and vitreous
Aug 20, 2025
BACKGROUND: Visual recovery after macula-off rhegmatogenous retinal detachment (RRD) remains limited in many cases, largely due to photoreceptor damage. This study aimed to assess the predictive value of early outer retinal findings on optical cohere... read more
Journal of orthopaedic surgery and research
Aug 20, 2025
BACKGROUND: With the growing complexity of total hip arthroplasty (THA) for high hip dislocation (HHD), artificial intelligence (AI)-assisted three-dimensional (3D) preoperative planning has emerged as a promising tool to enhance surgical accuracy. T... read more
BackgroundBilling and coding for orthopaedic procedures is a complex process with thousands of procedure codes and associated modifiers in existence. Foot and ankle faces an additional challenge as it is among the highest variability regarding proced... read more
Zhonghua wai ke za zhi [Chinese journal of surgery]
Aug 20, 2025
The complex anatomical structure of abdominal organs demands high precision in surgical procedures, which also increases postoperative complication risks. Advancements in digital medicine have created new opportunities for precision surgery. This art... read more
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