[Reproduction of a model of "two-hit" sepsis model with complication of pneumonia in rat].
Journal:
Zhonghua wei zhong bing ji jiu yi xue
PMID:
27132442
Abstract
OBJECTIVE: To reproduce a clinically relevant "two-hit" model of sepsis complicated by pneumonia and to explore the correlation between "two-hit" and immune state.
Authors
Keywords
Alanine Transaminase
Animals
Apoptosis
Aspartate Aminotransferases
Blood Urea Nitrogen
Creatinine
Disease Models, Animal
HMGB1 Protein
Interleukin-1beta
Interleukin-6
Male
Pneumonia
Random Allocation
Rats
Rats, Sprague-Dawley
Receptors, Tumor Necrosis Factor, Type I
Sepsis
Spleen
Transforming Growth Factor beta1
Tumor Necrosis Factor-alpha