AIMC Topic: Receptors, Tumor Necrosis Factor, Type I

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Machine intelligence identifies soluble TNFa as a therapeutic target for spinal cord injury.

Scientific reports Feb 9, 2021
Traumatic spinal cord injury (SCI) produces a complex syndrome that is expressed across multiple endpoints ranging from molecular and cellular changes to functional behavioral deficits. Effective therapeutic strategies for CNS injury are therefore li...
Disease Models, Animal Models, Neurological Recombinant Proteins Rats Receptors, Tumor Necrosis Factor, Type I Rats, Long-Evans Injections, Spinal Spinal Cord Injuries Artificial Intelligence Tumor Necrosis Factor-alpha Female Animals
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Machine Learning Classifier Models Can Identify Acute Respiratory Distress Syndrome Phenotypes Using Readily Available Clinical Data.

American journal of respiratory and critical care medicine Oct 1, 2020
Two distinct phenotypes of acute respiratory distress syndrome (ARDS) with differential clinical outcomes and responses to randomly assigned treatment have consistently been identified in randomized controlled trial cohorts using latent class analys...
Bilirubin Pulmonary Ventilation Plasminogen Activator Inhibitor 1 Platelet Count Mortality Bicarbonates Vital Signs Serum Albumin Intercellular Adhesion Molecule-1 Creatinine Vasoconstrictor Agents Carbon Dioxide Interleukin-8 Oxygen Blood Pressure Area Under Curve Humans Machine Learning Phenotype Interleukin-6 Partial Pressure Protein C Latent Class Analysis Age Factors Leukocyte Count Prognosis Inflammation Randomized Controlled Trials as Topic Respiratory Distress Syndrome Receptors, Tumor Necrosis Factor, Type I Biomarkers, Tumor Tidal Volume
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[Reproduction of a model of "two-hit" sepsis model with complication of pneumonia in rat].

Zhonghua wei zhong bing ji jiu yi xue Oct 1, 2015
OBJECTIVE: To reproduce a clinically relevant "two-hit" model of sepsis complicated by pneumonia and to explore the correlation between "two-hit" and immune state.
Sepsis Blood Urea Nitrogen Rats Receptors, Tumor Necrosis Factor, Type I Rats, Sprague-Dawley Random Allocation Disease Models, Animal Spleen HMGB1 Protein Animals Apoptosis Male Interleukin-1beta Pneumonia Alanine Transaminase Tumor Necrosis Factor-alpha Transforming Growth Factor beta1 Interleukin-6 Aspartate Aminotransferases Creatinine
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