Cytometry. Part A : the journal of the International Society for Analytical Cytology
Apr 17, 2025
The recent increase in the dimensionality of cytometry data has led to the development of various computational analysis methods. FlowSOM is one of the best-performing clustering methods but has room for improvement in terms of the consistency and sp...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Mar 10, 2025
Although flow cytometry produces reliable results, the data processing from gating to fingerprinting is prone to subjective bias. Here, we integrated autogating with Automated Machine Learning in flow cytometry to enhance the classification of bacter...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Sep 9, 2024
Erythrophagocytosis is a process consisting of recognition, engulfment and digestion by phagocytes of antibody-coated or damaged erythrocytes. Understanding the dynamics that are behind erythrophagocytosis is fundamental to comprehend this cellular p...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Aug 5, 2024
Imaging flow cytometry, which combines the advantages of flow cytometry and microscopy, has emerged as a powerful tool for cell analysis in various biomedical fields such as cancer detection. In this study, we develop multiplex imaging flow cytometry...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Apr 2, 2024
Deep learning approaches have frequently been used in the classification and segmentation of human peripheral blood cells. The common feature of previous studies was that they used more than one dataset, but used them separately. No study has been fo...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Feb 29, 2024
The gold standard of leukocyte differentiation is a manual examination of blood smears, which is not only time and labor intensive but also susceptible to human error. As to automatic classification, there is still no comparative study of cell segmen...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Feb 22, 2024
Circulating hybrid cells (CHCs) are a newly discovered, tumor-derived cell population found in the peripheral blood of cancer patients and are thought to contribute to tumor metastasis. However, identifying CHCs by immunofluorescence (IF) imaging of ...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Feb 15, 2024
Imaging flow cytometry is an attractive method to investigate individual cells by optical properties. However, imaging flow cytometry applications with clinical relevance are scarce so far. Platelet aggregation naturally occurs during blood coagulati...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Jan 4, 2024
The differential of leukocytes functions as the first indicator in clinical examinations. However, microscopic examinations suffered from key limitations of low throughputs in classifying leukocytes while commercially available hematology analyzers f...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Oct 10, 2023
This paper reported a micro flow cytometer capable of high-throughput characterization of single-cell electrical and structural features based on constrictional microchannels and deep neural networks. When single cells traveled through microchannels ...