Interdisciplinary sciences, computational life sciences
May 11, 2020
Malaria is one of the epidemics that can cause human death. Accurate and rapid diagnosis of malaria is important for treatment. Due to the limited number of data and human factors, the prediction performance and reliability of traditional classificat...
Interdisciplinary sciences, computational life sciences
Nov 18, 2019
The argonaute protein (Ago) exists in almost all organisms. In eukaryotes, it functions as a regulatory system for gene expression. In prokaryotes, it is a type of defense system against foreign invasive genomes. The Ago system has been engineered fo...
Interdisciplinary sciences, computational life sciences
Sep 4, 2019
BACKGROUND: Computational prediction of inhibition efficiency (IE) for inhibitor molecules is a crucial supplementary way to design novel molecules that can efficiently inhibit corrosion onto metallic surfaces.
Interdisciplinary sciences, computational life sciences
Jul 10, 2019
We present an application to melanoma detection of a multiple instance learning (MIL) approach, whose objective, in the binary case, is to discriminate between positive and negative sets of items. In the MIL terminology these sets are called bags and...
Interdisciplinary sciences, computational life sciences
Feb 21, 2019
Many scientific applications entail solving the subgraph isomorphism problem, i.e., given an input pattern graph, find all the subgraphs of a (usually much larger) target graph that are structurally equivalent to that input. Because subgraph isomorph...
Interdisciplinary sciences, computational life sciences
Mar 28, 2018
Flower Pollination Algorithm (FPA) has increasingly attracted researchers' attention in the computational intelligence field. This is due to its simplicity and efficiency in searching for global optimality of many optimization problems. However, ther...
Interdisciplinary sciences, computational life sciences
Jan 30, 2018
Interaction of multiple genetic variants is a major challenge in the development of effective treatment strategies for complex disorders. Identifying the most promising genes enhances the understanding of the underlying mechanisms of the disease, whi...
Interdisciplinary sciences, computational life sciences
Jan 29, 2018
Essential hypertension (EH) has become a major chronic disease around the world. To build a risk-predicting model for EH can help to interpose people's lifestyle and dietary habit to decrease the risk of getting EH. In this study, we constructed a EH...
Interdisciplinary sciences, computational life sciences
Dec 13, 2017
Acetylcholine esterase (AChE) is one of the targeted enzymes in the therapy of important neurodegenerative diseases such as Alzheimer's disease. Many studies on carbazole- and oxazolone-based compounds have been conducted in the last decade due to th...
Interdisciplinary sciences, computational life sciences
Jul 26, 2017
BACKGROUND: The identification of genetic regulatory networks (GRNs) provides insights into complex cellular processes. A class of recurrent neural networks (RNNs) captures the dynamics of GRN. Algorithms combining the RNN and machine learning scheme...