AIMC Topic: Argonaute Proteins

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Deep Learning-Assisted Fluorescence Single-Particle Detection of Fumonisin B Powered by Entropy-Driven Catalysis and Argonaute.

Analytical chemistry Jan 27, 2025
Timely and accurate detection of trace mycotoxins in agricultural products and food is significant for ensuring food safety and public health. Herein, a deep learning-assisted and entropy-driven catalysis (EDC)-Argonaute powered fluorescence single-p...
Fluorescence Deep Learning Aptamers, Nucleotide Biosensing Techniques Food Contamination Limit of Detection Spectrometry, Fluorescence Catalysis Fumonisins DNA, Single-Stranded Microspheres Entropy Argonaute Proteins
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Mesophilic Argonaute-Mediated Polydisperse Droplet Biosensor for Amplification-Free, One-Pot, and Multiplexed Nucleic Acid Detection Using Deep Learning.

Analytical chemistry Jan 23, 2024
Detection of nucleic acids from a single multiplexed and amplification-free test is critical for ensuring food safety, clinical diagnostics, and environmental monitoring. In this study, we introduced a mesophilic Argonaute protein from (CbAgo), whic...
Deep Learning Biosensing Techniques Nucleic Acid Amplification Techniques DNA Nucleic Acids Argonaute Proteins
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miRBind: A Deep Learning Method for miRNA Binding Classification.

Genes Dec 9, 2022
The binding of microRNAs (miRNAs) to their target sites is a complex process, mediated by the Argonaute (Ago) family of proteins. The prediction of miRNA:target site binding is an important first step for any miRNA target prediction algorithm. To dat...
Algorithms Deep Learning Computational Biology MicroRNAs Argonaute Proteins
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AGONOTES: A Robot Annotator for Argonaute Proteins.

Interdisciplinary sciences, computational life sciences Nov 18, 2019
The argonaute protein (Ago) exists in almost all organisms. In eukaryotes, it functions as a regulatory system for gene expression. In prokaryotes, it is a type of defense system against foreign invasive genomes. The Ago system has been engineered fo...
Algorithms Computational Biology Robotics Amino Acid Sequence Prokaryotic Cells Argonaute Proteins
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A deep learning framework to predict binding preference of RNA constituents on protein surface.

Nature communications Oct 30, 2019
Protein-RNA interaction plays important roles in post-transcriptional regulation. However, the task of predicting these interactions given a protein structure is difficult. Here we show that, by leveraging a deep learning model NucleicNet, attributes...
Humans Animals Deep Learning ROC Curve Protein Binding Mice RNA-Binding Proteins Area Under Curve RNA, Small Interfering RNA Phosphates Uracil Guanine Gene Knockdown Techniques Adenine Ribonuclease III Argonaute Proteins Cytosine Ribose
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