International journal of data mining and bioinformatics
Jan 1, 2015
Genome-wide Association Studies (GWAS) have resulted in many discovered risk variants for several obesity-related traits. However, before clinical relevance of these discoveries can be achieved, molecular or physiological mechanisms of these risk var...
International journal of data mining and bioinformatics
Jan 1, 2015
To date, classification of structural class using local protein structure rather than the whole structure has been gaining widespread attention. It is noted that the structural class lies in local composition or arrangement of secondary structure, wh...
International journal of data mining and bioinformatics
Jan 1, 2015
Real-Time Quantitative Polymerase Chain Reaction (qRT-PCR) is widely used in biological research. It is a key to the availability of qRT-PCR experiment to select a stable reference gene. However, selecting an appropriate reference gene usually requir...
International journal of data mining and bioinformatics
Jan 1, 2015
Detection of disease biomarkers in general and cancer biomarkers in particular is an important task which has received considerable attention in the area of in silico genomic experiments. We describe a new approach for detecting cancer biomarkers bas...
International journal of data mining and bioinformatics
Jan 1, 2015
The main purpose of traditional classification algorithms on bioinformatics application is to acquire better classification accuracy. However, these algorithms cannot meet the requirement that minimises the average misclassification cost. In this pap...
International journal of data mining and bioinformatics
Jan 1, 2015
Class imbalance learning has recently drawn considerable attention among researchers. In this area, a rare class is the class of primary interest from the aim of classification. Unfortunately, traditional machine learning algorithms fail to detect th...
International journal of data mining and bioinformatics
Jan 1, 2015
Protein superfamily classification deals with the problem of predicting the family membership of newly discovered amino acid sequence. Although many trivial alignment methods are already developed by previous researchers, but the present trend demand...
International journal of data mining and bioinformatics
Jan 1, 2015
Early classification of time series has been receiving a lot of attention recently. In this paper we present a model, which we call the Early Classification Model (ECM), that allows for early, accurate and patient-specific classification of multivari...
International journal of data mining and bioinformatics
Jan 1, 2015
Named Entity Recognition and Classification (NERC) is an important task in information extraction for biomedicine domain. Biomedical Named Entities include mentions of proteins, genes, DNA, RNA, etc. which, in general, have complex structures and are...
International journal of data mining and bioinformatics
Jan 1, 2015
The Resource Description Framework (RDF) is widely used for sharing biomedical data, such as gene ontology or the online protein database UniProt. SPARQL is a native query language for RDF, featuring regular expressions in queries for which exact val...