Journal of computational biology : a journal of computational molecular cell biology
Jul 25, 2024
Research on drug-drug interaction (DDI) prediction, particularly in identifying DDI event types, is crucial for understanding adverse drug reactions and drug combinations. This work introduces a Bidirectional Recurrent Neural Network model for DDI ev...
Journal of computational biology : a journal of computational molecular cell biology
Jul 8, 2024
Pseudoprogression (PSP) is a related reaction of glioblastoma treatment, and misdiagnosis can lead to unnecessary intervention. Magnetic resonance imaging (MRI) provides cross-modality images for PSP prediction studies. However, how to effectively us...
Journal of computational biology : a journal of computational molecular cell biology
Jun 27, 2024
The prompt and precise identification and delineation of tumor regions within glioma brain images are critical for mitigating the risks associated with this life-threatening ailment. In this study, we employ the UNet convolutional neural network (CNN...
Journal of computational biology : a journal of computational molecular cell biology
Jun 26, 2024
Noncoding RNA (NcRNA)-protein interactions (NPIs) play fundamentally important roles in carrying out cellular activities. Although various predictors based on molecular features and graphs have been published to boost the identification of NPIs, most...
Journal of computational biology : a journal of computational molecular cell biology
Jun 5, 2024
Automatic radiology medical report generation is a necessary development of artificial intelligence technology in the health care. This technology serves to aid doctors in producing comprehensive diagnostic reports, alleviating the burdensome workloa...
Journal of computational biology : a journal of computational molecular cell biology
Jan 4, 2024
Single-cell data afford unprecedented insights into molecular processes. But the complexity and size of these data sets have proved challenging and given rise to a large armory of statistical and machine learning approaches. The majority of approache...
Journal of computational biology : a journal of computational molecular cell biology
Dec 13, 2023
Using wet experimental methods to discover new thermophilic proteins or improve protein thermostability is time-consuming and expensive. Machine learning methods have shown powerful performance in the study of protein thermostability in recent years....
Journal of computational biology : a journal of computational molecular cell biology
Nov 28, 2023
Intratumoral heterogeneity and the presence of cancer stem cells are challenging issues in cancer therapy. An appropriate quantification of the stemness of individual cells for assessing the potential for self-renewal and differentiation from the cel...