Proceedings of the National Academy of Sciences of the United States of America
Aug 18, 2022
Proceedings of the National Academy of Sciences of the United States of America
Aug 15, 2022
There is growing evidence for the role of DNA methylation (DNAm) quantitative trait loci (mQTLs) in the genetics of complex traits, including psychiatric disorders. However, due to extensive linkage disequilibrium (LD) of the genome, it is challengin...
Proceedings of the National Academy of Sciences of the United States of America
Aug 15, 2022
Untethered soft miniature robots capable of accessing hard-to-reach regions can enable new, disruptive, and minimally invasive medical procedures. However, once the control input is removed, these robots easily move from their target location because...
Proceedings of the National Academy of Sciences of the United States of America
Aug 15, 2022
Testing the significance of predictors in a regression model is one of the most important topics in statistics. This problem is especially difficult without any parametric assumptions on the data. This paper aims to test the null hypothesis that give...
Proceedings of the National Academy of Sciences of the United States of America
Aug 10, 2022
We propose that coding and decoding in the brain are achieved through digital computation using three principles: relative ordinal coding of inputs, random connections between neurons, and belief voting. Due to randomization and despite the coarsenes...
Proceedings of the National Academy of Sciences of the United States of America
Aug 9, 2022
Many natural organisms, such as fungal hyphae and plant roots, grow at their tips, enabling the generation of complex bodies composed of natural materials as well as dexterous movement and exploration. Tip growth presents an exemplary process by whic...
Proceedings of the National Academy of Sciences of the United States of America
Aug 4, 2022
Using simulations or experiments performed at some set of temperatures to learn about the physics or chemistry at some other arbitrary temperature is a problem of immense practical and theoretical relevance. Here we develop a framework based on stati...
Proceedings of the National Academy of Sciences of the United States of America
Aug 3, 2022
Understanding spoken language requires transforming ambiguous acoustic streams into a hierarchy of representations, from phonemes to meaning. It has been suggested that the brain uses prediction to guide the interpretation of incoming input. However,...
Proceedings of the National Academy of Sciences of the United States of America
Aug 2, 2022
We demonstrate that a neural network pretrained on text and fine-tuned on code solves mathematics course problems, explains solutions, and generates questions at a human level. We automatically synthesize programs using few-shot learning and OpenAI's...
Proceedings of the National Academy of Sciences of the United States of America
Aug 1, 2022
A fundamental understanding of extracellular microenvironments of O and reactive oxygen species (ROS) such as HO, ubiquitous in microbiology, demands high-throughput methods of mimicking, controlling, and perturbing gradients of O and HO at microscop...