AIMC Topic: 2-Hydroxypropyl-beta-cyclodextrin

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Artificial intelligence-driven hydrogel microneedle patches integrating 5-fluorouracil inclusion complex-loaded flexible pegylated liposomes for enhanced non-melanoma skin cancer treatment.

International journal of pharmaceutics Dec 13, 2024
The current study focused on the development of crosslinked hydrogel microneedle patches (cHMNs) incorporating 5-FU-hydroxypropyl beta-cyclodextrin inclusion complex-loaded flexible PEGylated liposomes (5-FU-HPβCD-loaded FP-LPs) to enhance treatment ...
Humans Artificial Intelligence Skin Neoplasms Drug Delivery Systems Animals Cell Line, Tumor Mice Skin Fluorouracil Polyethylene Glycols Hydrogels Liposomes Administration, Cutaneous Needles Antimetabolites, Antineoplastic 2-Hydroxypropyl-beta-cyclodextrin Skin Absorption Transdermal Patch
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Pharmacokinetic comparison of different flubendazole formulations in pigs: A further contribution to its development as a macrofilaricide molecule.

International journal for parasitology. Drugs and drug resistance Sep 25, 2015
Despite the well established ivermectin activity against microfilaria, the success of human filariasis control programmes requires the use of a macrofilaricide compound. Different in vivo trials suggest that flubendazole (FLBZ), an anthelmintic benzi...
Animals Swine Injections, Subcutaneous Carboxymethylcellulose Sodium Administration, Oral Cross-Over Studies Anthelmintics Mebendazole Dosage Forms 2-Hydroxypropyl-beta-cyclodextrin Polysorbates
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