AIMC Topic: Transdermal Patch

Clear Filters Showing 1 to 5 of 5 articles

Development of a rapid detection method for patch thickness based on machine vision and near infrared spectroscopy: a case study of curcumin patch.

International journal of pharmaceutics Dec 22, 2025
Patches represent a significant dosage form within transdermal drug delivery systems. In the quality control of transdermal patches, thickness not only affects the drug loading per unit area and drug release behavior but also is associated with patie...
Algorithms Drug Delivery Systems Neural Networks, Computer Drug Liberation Administration, Cutaneous Transdermal Patch Spectroscopy, Near-Infrared Curcumin
View on PubMed DOI

Artificial intelligence-driven hydrogel microneedle patches integrating 5-fluorouracil inclusion complex-loaded flexible pegylated liposomes for enhanced non-melanoma skin cancer treatment.

International journal of pharmaceutics Dec 13, 2024
The current study focused on the development of crosslinked hydrogel microneedle patches (cHMNs) incorporating 5-FU-hydroxypropyl beta-cyclodextrin inclusion complex-loaded flexible PEGylated liposomes (5-FU-HPβCD-loaded FP-LPs) to enhance treatment ...
Artificial Intelligence Skin Neoplasms Humans Cell Line, Tumor Mice Skin Drug Delivery Systems Animals Transdermal Patch Administration, Cutaneous Needles 2-Hydroxypropyl-beta-cyclodextrin Hydrogels Antimetabolites, Antineoplastic Skin Absorption Liposomes Fluorouracil Polyethylene Glycols
View on PubMed DOI

Development and comparison of machine learning models for in-vitro drug permeation prediction from microneedle patch.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V May 6, 2024
The field of machine learning (ML) is advancing to a larger extent and finding its applications across numerous fields. ML has the potential to optimize the development process of microneedle patch by predicting the drug release pattern prior to its ...
Transdermal Patch Administration, Cutaneous Needles Skin Absorption Microinjections Permeability Drug Liberation Animals Skin Machine Learning Drug Delivery Systems Neural Networks, Computer
View on PubMed DOI

Biphasic burst and sustained transdermal delivery in vivo using an AI-optimized 3D-printed MN patch.

International journal of pharmaceutics Feb 6, 2023
The objective of the present study was to fabricate microneedles for delivering lipophilic active ingredients (APIs) using digital light processing (DLP) printing technology and quality by design (QbD) supplemented by artificial intelligence (AI) alg...
Drug Delivery Systems Ibuprofen Humans Animals Transdermal Patch Artificial Intelligence Rats Administration, Cutaneous Skin Printing, Three-Dimensional Needles Pharmaceutical Preparations
View on PubMed DOI

Lidocaine 5% Patch for Treatment of Acute Pain After Robotic Cardiac Surgery and Prevention of Persistent Incisional Pain: A Randomized, Placebo-Controlled, Double-Blind Trial.

Pain medicine (Malden, Mass.) Jul 14, 2015
OBJECTIVES: To test the hypotheses that lidocaine 5% patches decrease the severity of acute pain and incidence of persistent incisional pain after robotic cardiac valve surgery.
Acute Pain Transdermal Patch Middle Aged Double-Blind Method Lidocaine Aged Humans Pain, Postoperative Anesthetics, Local Analgesia, Patient-Controlled Male Female Pain Measurement Robotics Patient Satisfaction Analgesics, Opioid Disability Evaluation Heart Valves Cardiac Surgical Procedures
View on PubMed DOI
Popular Topics
Recent Journals