AIMC Topic: Adverse Childhood Experiences

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Multi-omics analysis reveal clinical-gut-brain interactions in female ibs patients with adverse childhood experiences.

Biology of sex differences
BACKGROUND: The brain-gut system, which involves bidirectional communication between the central nervous system and the gut, plays a central role in stress responses. Its dysregulation is implicated in irritable bowel syndrome (IBS), a stress-sensiti...

Exposotypes in psychotic disorders.

Scientific reports
Psychiatry lags in adopting etiological approaches to diagnosis, prognosis, and outcome prediction compared to the rest of medicine. Etiological factors such as childhood trauma (CHT), substance use (SU), and socioeconomic status (SES) significantly ...

Childhood trauma and adolescent anxiety: Uncovering emotion regulation pathways through integrated machine learning and traditional statistics.

Psychiatry research
Childhood trauma constitutes a significant risk factor for adolescent anxiety, with emotion regulation playing a critical role. This large-scale longitudinal study (N = 2461 at baseline, with external validation) examined differential relationships b...

Domestic violence and childhood trauma among married women using machine learning approach: a cross-sectional study.

BMC public health
BACKGROUND: Globally, 27% of ever-partnered women aged 15-49 have experienced physical, sexual, or intimate partner violence at least once in their lifetime. In Saudi Arabia, domestic violence (DV) remains a concern despite cultural and economic adva...

Can adverse childhood experiences predict chronic health conditions? Development of trauma-informed, explainable machine learning models.

Frontiers in public health
INTRODUCTION: Decades of research have established the association between adverse childhood experiences (ACEs) and adult onset of chronic diseases, influenced by health behaviors and social determinants of health (SDoH). Machine Learning (ML) is a p...

AI-Driven Care Navigation to Foster Early Childhood Resilience and Positive Childhood Experiences.

Studies in health technology and informatics
Early life experiences are crucial for health and well-being, influencing physical, emotional, and social development throughout the lifespan. Recent research shows that Positive Childhood Experiences (PCEs), such as access to supportive environments...

Identifying Preliminary Risk Profiles for Dissociation in 16- to 25-Year-Olds Using Machine Learning.

Early intervention in psychiatry
INTRODUCTION: Dissociation is associated with clinical severity, increased risk of suicide and self-harm, and disproportionately affects adolescents and young adults. Whilst evidence indicates multiple factors contribute to dissociative experiences, ...