IEEE/ACM transactions on computational biology and bioinformatics
Aug 6, 2021
The identification of drug-target interactions (DTIs) is an essential step in the process of drug discovery. As experimental validation suffers from high cost and low success rate, various computational models have been exploited to infer potential D...
IEEE/ACM transactions on computational biology and bioinformatics
Aug 6, 2021
In December of 2019, a novel coronavirus (COVID-19) appeared in Wuhan city, China and has been reported in many countries with millions of people infected within only four months. Chest computed Tomography (CT) has proven to be a useful supplement to...
IEEE/ACM transactions on computational biology and bioinformatics
Aug 6, 2021
DNA-binding proteins (DBPs) and RNA-binding proteins (RBPs) are two kinds of crucial proteins, which are associated with various cellule activities and some important diseases. Accurate identification of DBPs and RBPs facilitate both theoretical rese...
IEEE/ACM transactions on computational biology and bioinformatics
Aug 6, 2021
Topological data analysis (TDA) is a powerful method for reducing data dimensionality, mining underlying data relationships, and intuitively representing the data structure. The Mapper algorithm is one such tool that projects high-dimensional data to...
IEEE/ACM transactions on computational biology and bioinformatics
Aug 6, 2021
With a variety of tumor subtypes, personalized treatments need to identify the subtype of a tumor as accurately as possible. The development of DNA microarrays provides an opportunity to predict tumor classification. One strategy is to use gene expre...
IEEE/ACM transactions on computational biology and bioinformatics
Aug 6, 2021
Reconstruction of time-varying gene regulatory networks underlying a time-series gene expression data is a fundamental challenge in the computational systems biology. The challenge increases multi-fold if the target networks need to be constructed fo...
IEEE/ACM transactions on computational biology and bioinformatics
Aug 6, 2021
Life threatening diseases like adult T-cell leukemia, neurodegenerative diseases, and demyelinating diseases such as HTLV-1 based myelopathy/tropical spastic paraparesis (HAM/TSP), hypocalcaemia, and bone lesions are caused by a group of human retrov...
IEEE/ACM transactions on computational biology and bioinformatics
Aug 6, 2021
Biological targets are most commonly proteins such as enzymes, ion channels, and receptors. They are anything within a living organism to bind with some other entities (like an endogenous ligand or a drug), resulting in change in their behaviors or f...
Although artificial intelligence models have demonstrated high accuracy in identifying specific orthopedic implant models from imaging, which is an important and time-consuming task, the scope of prior works and performance of prior models have not b...
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin
Aug 5, 2021
PURPOSE:  Since artificial intelligence is transitioning from an experimental stage to clinical implementation, the aim of our study was to evaluate the performance of a commercial, computer-aided detection algorithm of computed tomography pulmonary ...
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