IEEE/ACM transactions on computational biology and bioinformatics
Mar 7, 2019
Antimicrobial peptides are short amino acid sequences that may be antibacterial, antifungal, and antiviral. Most machine learning methodologies applied to identifying antibacterial peptides have developed feature vectors of identical lengths for each...
Measuring drug-drug similarity is important but challenging. Significant progresses have been made in drugs whose labeled training data is sufficient and available. However, handling data skewness and incompleteness with domain-specific knowledge gra...
Journal of chemical information and modeling
Mar 4, 2019
Predicting the activity of new chemical compounds over pathogenic microorganisms with different metabolic reaction networks (MRN ) is an important goal due to the different susceptibility to antibiotics. The ChEMBL database contains >160 000 outcomes...
This study trained long short-term memory (LSTM) recurrent neural networks (RNNs) incorporating an attention mechanism to predict daily sepsis, myocardial infarction (MI), and vancomycin antibiotic administration over two week patient ICU courses in ...
Artificial cells, nanomedicine, and biotechnology
Jan 28, 2019
Cancer incidence is still increasing due to inadequate responsive treatments. Inertness and biocompatibility of nanoparticles synthesized using plant extracts have shown therapeutic applications and make it to be a good anti-cancer candidates. This s...
Polyphenols are known for their antimicrobial activity, whilst both polyphenols and the globular protein β-lactoglobulin (bLG) are suggested to have antioxidant properties and promote cell proliferation. These are potentially useful properties for a ...
European journal of hospital pharmacy : science and practice
Jan 13, 2019
OBJECTIVES: To determine the influence of different buffers, pH and meropenem concentrations on the degradation rates of meropenem in aqueous solution during storage at 32°C, with the aim of developing a formulation suitable for 24-hour infusion in a...
. Lactic acid bacteria (LAB) were isolated from fermented foods, such as glutinous rice dough, corn noodle, chili sauce, potherb mustard pickles, and stinky tofu, in northeast China. LAB strains with antimicrobial activities were screened, and seven ...
Materials science & engineering. C, Materials for biological applications
Dec 29, 2018
Plant diseases are threat to global food security. The excessive use of agrochemicals is the leading cause of pesticides resistance and toxicity to beneficial life forms. The quest for innocuous and alternate antimicrobial agent is crucial in order t...
Veterinary journal (London, England : 1997)
Dec 29, 2018
Disposition of ceftizoxime was studied in Indian crossbred cows following a single IV dosing in field conditions. Six healthy lactating and six mastitic crossbred cows were assigned to two groups (Group 1 and Group 2). A single IV administration of c...