AIMC Topic: Antibodies

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Antibody interface prediction with 3D Zernike descriptors and SVM.

Bioinformatics (Oxford, England) Jun 1, 2019
MOTIVATION: Antibodies are a class of proteins capable of specifically recognizing and binding to a virtually infinite number of antigens. This binding malleability makes them the most valuable category of biopharmaceuticals for both diagnostic and t...
Software Support Vector Machine Proteins Amino Acids Antibodies
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Sphinx: merging knowledge-based and ab initio approaches to improve protein loop prediction.

Bioinformatics (Oxford, England) May 1, 2017
MOTIVATION: Loops are often vital for protein function, however, their irregular structures make them difficult to model accurately. Current loop modelling algorithms can mostly be divided into two categories: knowledge-based, where databases of frag...
Software Algorithms Animals Computational Biology Models, Molecular Antibodies Knowledge Bases Protein Conformation
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High Mobility Group Box 1 Protein Enhances HIV Replication in Newly Infected Primary T Cells.

Clinical laboratory Dec 1, 2016
BACKGROUND: High-mobility group box 1 (HMGB1), a DNA-binding protein, has recently been shown to have effects on HIV replication, but the effects are dependent on the cell type and the timing of infection. Using human primary T cells, this study aime...
Humans Cells, Cultured T-Lymphocytes HIV Infections Time Factors Cell Proliferation Signal Transduction HMGB1 Protein Antibodies HIV-1 Transfection Host-Pathogen Interactions Virus Replication HIV Core Protein p24 Primary Cell Culture
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