AIMC Topic: Mice, SCID

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Propofol affects the growth and metastasis of pancreatic cancer via ADAM8.

Pharmacological reports : PR Dec 20, 2019
BACKGROUND: Anesthesia is a major component of surgery and recently considered an important regulator of cell phenotypes. Here we aimed to investigate propofol, an anesthesia drug, in suppressing pancreatic cancer (PDAC), focusing on A disintegrin an...
Mice, SCID Pancreatic Neoplasms Matrix Metalloproteinase 9 Apoptosis Neoplasm Invasiveness Neoplasm Metastasis Matrix Metalloproteinase 2 Xenograft Model Antitumor Assays Antineoplastic Agents Humans Cell Line, Tumor Membrane Proteins Animals MAP Kinase Signaling System Cell Proliferation Propofol ADAM Proteins Cell Movement
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Machine learning improves classification of preclinical models of pancreatic cancer with chemical exchange saturation transfer MRI.

Magnetic resonance in medicine Sep 17, 2018
PURPOSE: We sought to assess whether machine learning-based classification approaches can improve the classification of pancreatic tumor models relative to more simplistic analysis methods, using T relaxation, CEST, and DCE MRI.
Magnetic Resonance Imaging Pancreatic Neoplasms Image Processing, Computer-Assisted Mice Hypoxia Image Interpretation, Computer-Assisted Mice, SCID Principal Component Analysis Area Under Curve Reproducibility of Results Sensitivity and Specificity Animals Cell Line, Tumor Algorithms Female Humans Image Enhancement Machine Learning Normal Distribution
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Deep Learning Reveals Cancer Metastasis and Therapeutic Antibody Targeting in the Entire Body.

Cell Dec 12, 2019
Reliable detection of disseminated tumor cells and of the biodistribution of tumor-targeting therapeutic antibodies within the entire body has long been needed to better understand and treat cancer metastasis. Here, we developed an integrated pipelin...
Mice, Nude Mice, Inbred C57BL Deep Learning Mice Neoplasm Metastasis Tumor Microenvironment MCF-7 Cells Mice, SCID Animals Antibodies Humans Neoplasms Drug Therapy, Computer-Assisted Software Diagnosis, Computer-Assisted
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[The Effect of Lipopolysaccharide-Induced Mouse B Cell Activation on Schistosoma japonicum Development].

Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases Oct 1, 2015
OBJECTIVE: To investigate the effect of lipopolysaccharide (LPS)-induced B cell activation on the development of Schistosoma japonicum.
T-Lymphocytes Male Lymphocyte Activation Mice Female Animals Cytokines B-Lymphocytes Schistosoma japonicum Mice, SCID Lipopolysaccharides Schistosomiasis japonica Spleen Mice, Nude Liver Mice, Inbred BALB C
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