AIMC Topic: ATP Binding Cassette Transporter, Subfamily G, Member 2

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Machine Learning Techniques Applied to the Study of Drug Transporters.

Molecules (Basel, Switzerland) Aug 8, 2023
With the advancement of computer technology, machine learning-based artificial intelligence technology has been increasingly integrated and applied in the fields of medicine, biology, and pharmacy, thereby facilitating their development. Transporters...
Artificial Intelligence Machine Learning Neoplasm Proteins Membrane Transport Proteins ATP Binding Cassette Transporter, Subfamily G, Member 2
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Direct Comparison of the Prediction of the Unbound Brain-to-Plasma Partitioning Utilizing Machine Learning Approach and Mechanistic Neuropharmacokinetic Model.

The AAPS journal May 18, 2021
The mechanistic neuropharmacokinetic (neuroPK) model was established to predict unbound brain-to-plasma partitioning (K) by considering in vitro efflux activities of multiple drug resistance 1 (MDR1) and breast cancer resistance protein (BCRP). Herei...
Machine Learning Blood-Brain Barrier Animals Male Rats Predictive Value of Tests Dogs Models, Biological Madin Darby Canine Kidney Cells Datasets as Topic Models, Animal ATP Binding Cassette Transporter, Subfamily B ATP Binding Cassette Transporter, Subfamily G, Member 2
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Association of ATP-Binding Cassette Transporter (ABC) Gene Polymorphisms with Viral Load in Patients with Genotype 1 Hepatitis C Virus Infection.

Clinical laboratory Sep 1, 2016
BACKGROUND: ATP-binding cassette transporters (ABC) gene polymorphisms are associated with various biological functions, including hepatitis C virus (HCV) infection. This study aims to explore the impact of ABC transporters polymorphisms on HCV viral...
Humans Female Male Middle Aged Viral Load Polymorphism, Single Nucleotide Genotype Lipoproteins Interleukins Neoplasm Proteins ATP Binding Cassette Transporter, Subfamily B, Member 1 Hepacivirus Hepatitis C, Chronic Gene Frequency ATP-Binding Cassette Transporters ATP Binding Cassette Transporter 1 ATP Binding Cassette Transporter, Subfamily B ATP Binding Cassette Transporter, Subfamily B, Member 11 ATP Binding Cassette Transporter, Subfamily G, Member 2 ATP Binding Cassette Transporter, Subfamily G, Member 5
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Classification of Breast Cancer Resistant Protein (BCRP) Inhibitors and Non-Inhibitors Using Machine Learning Approaches.

Combinatorial chemistry & high throughput screening Jan 1, 2015
The breast cancer resistant protein (BCRP) is an important transporter and its inhibitors play an important role in cancer treatment by improving the oral bioavailability as well as blood brain barrier (BBB) permeability of anticancer drugs. In this ...
Humans Neural Networks, Computer Machine Learning Neoplasm Proteins ATP-Binding Cassette Transporters ATP Binding Cassette Transporter, Subfamily G, Member 2
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