AIMC Topic: ATP Binding Cassette Transporter, Subfamily G, Member 2

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PyaiVS unifies AI workflows to accelerate ligand discovery and yields ABCG2 inhibitors.

European journal of medicinal chemistry Sep 17, 2025
Developing optimized AI models for virtual screening requires coordinated selection of algorithms, molecular representations, and data splitting strategies, yet lacks integrated tools. We present PyaiVS, a Python package that integrates nine machine ...
Neoplasm Proteins Structure-Activity Relationship Dose-Response Relationship, Drug Ligands ATP Binding Cassette Transporter, Subfamily G, Member 2 Molecular Structure Machine Learning Workflow Molecular Docking Simulation Drug Discovery Humans Antineoplastic Agents
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Machine Learning Techniques Applied to the Study of Drug Transporters.

Molecules (Basel, Switzerland) Aug 8, 2023
With the advancement of computer technology, machine learning-based artificial intelligence technology has been increasingly integrated and applied in the fields of medicine, biology, and pharmacy, thereby facilitating their development. Transporters...
Machine Learning Neoplasm Proteins Artificial Intelligence ATP Binding Cassette Transporter, Subfamily G, Member 2 Membrane Transport Proteins
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Direct Comparison of the Prediction of the Unbound Brain-to-Plasma Partitioning Utilizing Machine Learning Approach and Mechanistic Neuropharmacokinetic Model.

The AAPS journal May 18, 2021
The mechanistic neuropharmacokinetic (neuroPK) model was established to predict unbound brain-to-plasma partitioning (K) by considering in vitro efflux activities of multiple drug resistance 1 (MDR1) and breast cancer resistance protein (BCRP). Herei...
Models, Animal ATP Binding Cassette Transporter, Subfamily B Datasets as Topic ATP Binding Cassette Transporter, Subfamily G, Member 2 Predictive Value of Tests Dogs Models, Biological Madin Darby Canine Kidney Cells Male Rats Machine Learning Animals Blood-Brain Barrier
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Association of ATP-Binding Cassette Transporter (ABC) Gene Polymorphisms with Viral Load in Patients with Genotype 1 Hepatitis C Virus Infection.

Clinical laboratory Sep 1, 2016
BACKGROUND: ATP-binding cassette transporters (ABC) gene polymorphisms are associated with various biological functions, including hepatitis C virus (HCV) infection. This study aims to explore the impact of ABC transporters polymorphisms on HCV viral...
Interleukins Neoplasm Proteins Lipoproteins Hepatitis C, Chronic Gene Frequency ATP Binding Cassette Transporter, Subfamily B, Member 1 ATP Binding Cassette Transporter, Subfamily B, Member 11 Hepacivirus ATP Binding Cassette Transporter 1 ATP Binding Cassette Transporter, Subfamily G, Member 2 Female ATP Binding Cassette Transporter, Subfamily B ATP-Binding Cassette Transporters Middle Aged Humans ATP Binding Cassette Transporter, Subfamily G, Member 5 Male Polymorphism, Single Nucleotide Viral Load Genotype
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Classification of Breast Cancer Resistant Protein (BCRP) Inhibitors and Non-Inhibitors Using Machine Learning Approaches.

Combinatorial chemistry & high throughput screening Jan 1, 2015
The breast cancer resistant protein (BCRP) is an important transporter and its inhibitors play an important role in cancer treatment by improving the oral bioavailability as well as blood brain barrier (BBB) permeability of anticancer drugs. In this ...
Humans ATP-Binding Cassette Transporters ATP Binding Cassette Transporter, Subfamily G, Member 2 Machine Learning Neural Networks, Computer Neoplasm Proteins
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