AIMC Topic: Bacteriophages
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Identifying Phage Virion Proteins by Using Two-Step Feature Selection Methods.
Molecules (Basel, Switzerland)
Aug 10, 2018
Accurate identification of phage virion protein is not only a key step for understanding the function of the phage virion protein but also helpful for further understanding the lysis mechanism of the bacterial cell. Since traditional experimental met...
iPHLoc-ES: Identification of bacteriophage protein locations using evolutionary and structural features.
Journal of theoretical biology
Sep 21, 2017
Bacteriophage proteins are viruses that can significantly impact on the functioning of bacteria and can be used in phage based therapy. The functioning of Bacteriophage in the host bacteria depends on its location in those host cells. It is very impo...
Bacterial Virus Ontology; Coordinating across Databases.
Viruses
May 23, 2017
Bacterial viruses, also called bacteriophages, display a great genetic diversity and utilize unique processes for infecting and reproducing within a host cell. All these processes were investigated and indexed in the ViralZone knowledge base. To faci...
Endolysin LysSA97 is synergistic with carvacrol in controlling Staphylococcus aureus in foods.
International journal of food microbiology
Dec 27, 2016
LysSA97 is an endolysin encoded by the bacteriophage SA97, the genome sequence of which has been recently revealed. LysSA97 has lytic activity against a variety of Staphylococcus strains that cause foodborne illness. In order to improve its potential...
A solution to the postantibiotic era: phages as precision medicine.
Current opinion in microbiology
Aug 1, 2025
Antibiotic-resistant bacterial infections pose a significant global health challenge. Phage therapy provides a promising alternative to antibiotics that enables the specific targeting of pathogenic bacteria while preserving the healthy microbiome. Re...
[Methodological breakthroughs and challenges in research of soil phage microecology].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Jun 25, 2025
Phages, as obligate bacterial and archaeal parasites, constitute a virus group of paramount ecological significance due to their exceptional abundance and genetic diversity. These biological entities serve as critical regulators in Earth's ecosystems...
PharaCon: a new framework for identifying bacteriophages via conditional representation learning.
Bioinformatics (Oxford, England)
Mar 4, 2025
MOTIVATION: Identifying bacteriophages (phages) within metagenomic sequences is essential for understanding microbial community dynamics. Transformer-based foundation models have been successfully employed to address various biological challenges. Ho...
Predicting phage-host interactions via feature augmentation and regional graph convolution.
Briefings in bioinformatics
Nov 22, 2024
Identifying phage-host interactions (PHIs) is a crucial step in developing phage therapy, which is the promising solution to addressing the issue of antibiotic resistance in superbugs. However, the lifestyle of phages, which strongly depends on their...
DeepPBI-KG: a deep learning method for the prediction of phage-bacteria interactions based on key genes.
Briefings in bioinformatics
Sep 23, 2024
Phages, the natural predators of bacteria, were discovered more than 100 years ago. However, increasing antimicrobial resistance rates have revitalized phage research. Methods that are more time-consuming and efficient than wet-laboratory experiments...
DeePhafier: a phage lifestyle classifier using a multilayer self-attention neural network combining protein information.
Briefings in bioinformatics
Jul 25, 2024
Bacteriophages are the viruses that infect bacterial cells. They are the most diverse biological entities on earth and play important roles in microbiome. According to the phage lifestyle, phages can be divided into the virulent phages and the temper...
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