AIMC Topic: Basal Forebrain

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Multimodal neuroimaging unveils basal forebrain-limbic system circuit dysregulation in cognitive impairment with depression: a pathway to early diagnosis and intervention.

The journal of prevention of Alzheimer's disease Jul 16, 2025
BACKGROUND: Alzheimer's disease (AD) frequently co-occurs with depressive symptoms, exacerbating both cognitive decline and clinical complexity, yet the neural substrates linking this co-occurrence remain poorly understood. We aimed to investigate th...
Humans Biomarkers Female Aged Cross-Sectional Studies Male Middle Aged Depression Cognitive Dysfunction Magnetic Resonance Imaging Multimodal Imaging Early Diagnosis Neuroimaging Limbic System Basal Forebrain
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A deep learning toolbox for automatic segmentation of subcortical limbic structures from MRI images.

NeuroImage Sep 25, 2021
A tool was developed to automatically segment several subcortical limbic structures (nucleus accumbens, basal forebrain, septal nuclei, hypothalamus without mammillary bodies, the mammillary bodies, and fornix) using only a T1-weighted MRI as input. ...
Humans Female Reproducibility of Results Aged Aged, 80 and over Young Adult Adult Male Middle Aged Deep Learning Adolescent Magnetic Resonance Imaging Nucleus Accumbens Limbic System Septal Nuclei Basal Forebrain Fornix, Brain
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