MOTIVATION: Computational gene prioritization can aid in disease gene identification. Here, we propose pBRIT (prioritization using Bayesian Ridge regression and Information Theoretic model), a novel adaptive and scalable prioritization tool, integrat...
SUMMARY: Second use of clinical data commonly involves annotating biomedical text with terminologies and ontologies. The National Center for Biomedical Ontology Annotator is a frequently used annotation service, originally designed for biomedical dat...
MOTIVATION: The ever-increasing number of biomedical datasets provides tremendous opportunities for re-use but current data repositories provide limited means of exploration apart from text-based search. Ontological metadata annotations provide conte...
Studies in health technology and informatics
Jan 1, 2018
There are many drug databases, but sometimes the data quality may result in wrong medication for patients. Results that it is very important to provide a good quality drug information, supply structured information and build useful relations between ...
Studies in health technology and informatics
Jan 1, 2018
Optical navigation systems help surgeons find their way through the complex anatomy of a patient. However, such systems are accident-sensitive, time-consuming and difficult to use because of their complicated technical requirements such as the settin...
Studies in health technology and informatics
Jan 1, 2018
Metadata management is an important task in medical informatics and highly affects the gain out of existing health information data. Data Warehouse solutions like Informatics for Integrating Biology and the Bedside (i2b2) are common tools for identif...
Studies in health technology and informatics
Jan 1, 2018
Current medical systems need to be able to communicate complex and detailed medical data securely and efficiently. However, the quantity of available healthcare data is rising rapidly, far exceeding the capacity to deliver personal or public health b...
Studies in health technology and informatics
Jan 1, 2018
In the biomedical domain, there exist a number of common data models (CDM) that have experienced wide uptake. However, none of these has emerged as the common model. Recently, the demand for integrating and analyzing increasingly large data sets in c...
Studies in health technology and informatics
Jan 1, 2018
An ontology of care is a formal, explicit specification of a shared conceptualization. Constructing an ontology is a process that requires four elements: knowledge object, subject that knows, knowledge operation and result. These elements configure t...