AIMC Topic: Brain Neoplasms

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Metabolic signatures derived from whole-brain MR-spectroscopy identify early tumor progression in high-grade gliomas using machine learning.

Journal of neuro-oncology
PURPOSE: Recurrence for high-grade gliomas is inevitable despite maximal safe resection and adjuvant chemoradiation, and current imaging techniques fall short in predicting future progression. However, we introduce a novel whole-brain magnetic resona...

Sexually dimorphic computational histopathological signatures prognostic of overall survival in high-grade gliomas via deep learning.

Science advances
High-grade glioma (HGG) is an aggressive brain tumor. Sex is an important factor that differentially affects survival outcomes in HGG. We used an end-to-end deep learning approach on hematoxylin and eosin (H&E) scans to (i) identify sex-specific hist...

Artificial intelligence-assisted volume isotropic simultaneous interleaved bright- and black-blood examination for brain metastases.

Neuroradiology
PURPOSE: To verify the effectiveness of artificial intelligence-assisted volume isotropic simultaneous interleaved bright-/black-blood examination (AI-VISIBLE) for detecting brain metastases.

Reconstruct incomplete relation for incomplete modality brain tumor segmentation.

Neural networks : the official journal of the International Neural Network Society
Different brain tumor magnetic resonance imaging (MRI) modalities provide diverse tumor-specific information. Previous works have enhanced brain tumor segmentation performance by integrating multiple MRI modalities. However, multi-modal MRI data are ...

Ensemble learning-based pretreatment MRI radiomic model for distinguishing intracranial extraventricular ependymoma from glioblastoma multiforme.

NMR in biomedicine
This study aims to develop an ensemble learning (EL) method based on magnetic resonance (MR) radiomic features to preoperatively differentiate intracranial extraventricular ependymoma (IEE) from glioblastoma (GBM). This retrospective study enrolled p...

Utilizing machine learning to tailor radiotherapy and chemoradiotherapy for low-grade glioma patients.

PloS one
BACKGROUND: There is ongoing uncertainty about the effectiveness of various adjuvant treatments for low-grade gliomas (LGGs). Machine learning (ML) models that predict individual treatment effects (ITE) and provide treatment recommendations could hel...

Beyond hand-crafted features for pretherapeutic molecular status identification of pediatric low-grade gliomas.

Scientific reports
The use of targeted agents in the treatment of pediatric low-grade gliomas (pLGGs) relies on the determination of molecular status. It has been shown that genetic alterations in pLGG can be identified non-invasively using MRI-based radiomic features ...

Harnessing Deep Learning for Accurate Pathological Assessment of Brain Tumor Cell Types.

Journal of imaging informatics in medicine
Primary diffuse central nervous system large B-cell lymphoma (CNS-pDLBCL) and high-grade glioma (HGG) often present similarly, clinically and on imaging, making differentiation challenging. This similarity can complicate pathologists' diagnostic effo...

A deep-learning-based surrogate model for Monte-Carlo simulations of the linear energy transfer in primary brain tumor patients treated with proton-beam radiotherapy.

Physics in medicine and biology
This study explores the use of neural networks (NNs) as surrogate models for Monte-Carlo (MC) simulations in predicting the dose-averaged linear energy transfer (LET) of protons in proton-beam therapy based on the planned dose distribution and patien...

Neuro-XAI: Explainable deep learning framework based on deeplabV3+ and bayesian optimization for segmentation and classification of brain tumor in MRI scans.

Journal of neuroscience methods
The prevalence of brain tumor disorders is currently a global issue. In general, radiography, which includes a large number of images, is an efficient method for diagnosing these life-threatening disorders. The biggest issue in this area is that it t...