This study aimed to develop and validate an interpretable radiomics-based machine learning model using contrast-enhanced T1-weighted imaging (CE-T1WI) to differentiate glioblastoma (GB) from primary central nervous system lymphoma (PCNSL), while comp...
Primary large B-cell lymphomas of immune-privileged sites, including primary central nervous system lymphoma (PCNSL) and primary testicular lymphoma (PTL), exhibit distinct clinicopathologic features contributing to aggressive behavior and immune eva...
International journal of medical informatics
Jun 12, 2025
BACKGROUND AND OBJECTIVES: The treatment of central nervous system (CNS) tumors is complex and resource-intensive, with higher mortality in underserved regions. Large language models (LLMs) show promise in medical support, but their real-world perfor...
PURPOSE: To develop and evaluate radiomics-based models using contrast-enhanced T1-weighted imaging (CE-T1WI) for the non-invasive differentiation of primary central nervous system lymphoma (PCNSL) and solitary brain metastasis (SBM), aiming to impro...
The diagnosis and prognosis of Primary Central Nervous System Lymphoma (PCNSL) present significant challenges. In this study, the potential use of machine learning algorithms in diagnosing and predicting the prognosis for PCNSL based on cerebrospinal...
OBJECTIVES: To evaluate the role of multimodal magnetic resonance imaging radiomics features in predicting early recurrence of primary central nervous system lymphoma (PCNSL) and to investigate their correlation with patient prognosis.
The diagnostic landscape of brain tumors integrates comprehensive molecular markers alongside traditional histopathological evaluation. DNA methylation and next-generation sequencing (NGS) have become a cornerstone in central nervous system (CNS) tum...
PURPOSE: In primary central nervous system lymphoma (PCNSL), B-cell lymphoma-6 (BCL-6) is an unfavorable prognostic biomarker. We aim to non-invasively detect BCL-6 overexpression in PCNSL patients using multiparametric MRI and machine learning techn...
OBJECTIVE: Research into the effectiveness and applicability of deep learning, radiomics, and their integrated models based on Magnetic Resonance Imaging (MRI) for preoperative differentiation between Primary Central Nervous System Lymphoma (PCNSL) a...
PURPOSE: Artificial Intelligence (AI) has become increasingly integrated clinically within neurosurgical oncology. This report reviews the cutting-edge technologies impacting tumor treatment and outcomes.
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