Computer methods and programs in biomedicine
May 12, 2022
BACKGROUND AND OBJECTIVE: Breast density assessed from digital mammograms is a biomarker for higher risk of developing breast cancer. Experienced radiologists assess breast density using the Breast Image and Data System (BI-RADS) categories. Supervis...
BACKGROUND: Manually extracted data points from health records are collated on an institutional, provincial, and national level to facilitate clinical research. However, the labour-intensive clinical chart review process puts an increasing burden on ...
Being a second most cause of mortality worldwide, cancer has been identified as a perilous disease for human beings, where advance stage diagnosis may not help much in safeguarding patients from mortality. Thus, efforts to provide a sustainable archi...
Emerging liquid biopsy methods for investigating biomarkers in bodily fluids such as blood, saliva, or urine can be used to perform noninvasive cancer detection. However, the complexity and heterogeneity of exosomes require improved methods to achiev...
Breast cancer is regarded as the leading killer of women today. The early diagnosis and treatment of breast cancer is the key to improving the survival rate of patients. A method of breast cancer histopathological images recognition based on deep sem...
OBJECTIVE: To develop novel deep learning network (DLN) with the incorporation of the automatic segmentation network (ASN) for morphological analysis and determined the performance for diagnosis breast cancer in automated breast ultrasound (ABUS).
While essential to our understanding of solid tumor progression, the study of cell and tissue mechanics has yet to find traction in the clinic. Determining tissue stiffness, a mechanical property known to promote a malignant phenotype in vitro and in...
Cell deformability is a useful feature for diagnosing various diseases (e.g., the invasiveness of cancer cells). Existing methods commonly inflict pressure on cells and observe changes in cell areas, diameters, or thickness according to the degree of...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Apr 18, 2022
PURPOSE/OBJECTIVE(S): Precise segmentation of clinical target volumes (CTV) in breast cancer is indispensable for state-of-the art radiotherapy. Despite international guidelines, significant intra- and interobserver variability exists, negatively imp...
The advancement of highly multiplexed spatial technologies requires scalable methods that can leverage spatial information. We present MISTy, a flexible, scalable, and explainable machine learning framework for extracting relationships from any spati...
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