AIMC Topic: Calcification, Physiologic

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AI-Assisted Label-Free Monitoring Bone Mineral Metabolism on Demineralized Bone Paper.

ACS biomaterials science & engineering Mar 19, 2025
Effective drug development for bone-related diseases, such as osteoporosis and metastasis, is hindered by the lack of physiologically relevant in vitro models. Traditional platforms, including standard tissue culture plastic, fail to replicate the st...
Humans Artificial Intelligence Machine Learning Animals Mice Paper Osteogenesis Collagen Osteoblasts Bone and Bones Calcification, Physiologic Osteoclasts
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Comparative microstructural analysis of bone osteotomies after cutting by computer-assisted robot-guided laser osteotome and piezoelectric osteotome: an in vivo animal study.

Lasers in medical science Apr 13, 2018
Most industrial laser applications utilize computer and robot assistance, for guidance, safety, repeatability, and precision. In contrast, medical applications using laser systems are mostly conducted manually. The advantages can be effective only wh...
Animals Robotics Surgery, Computer-Assisted Osteotomy Sheep Lasers Bone and Bones Laser Therapy Calcification, Physiologic X-Ray Microtomography
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Alkaline phosphatase determines polyphosphate-induced mineralization in a cell-type independent manner.

Journal of bone and mineral metabolism Oct 16, 2015
Polyphosphate [Poly(P)] has positive effects on osteoblast mineralization; however, the underlying mechanism remains unclear. In addition, it is unknown whether Poly(P) promotes mineralization in soft tissues. We investigated this by using various ce...
Animals Mice Rats CHO Cells Cricetulus Alkaline Phosphatase 3T3-L1 Cells Osteoblasts Gene Expression Regulation, Enzymologic Organ Specificity Cricetinae Calcification, Physiologic Polyphosphates
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