AIMC Topic: Candidemia

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Quantification of spp. using fluorescence and SERS spectroscopy for bloodstream infection diagnosis.

Journal of materials chemistry. B
Bloodstream infections caused by spp. are among the leading hospital-acquired infections, but their diagnosis remains slow and challenging with conventional culture-based methods, which often require days to deliver results. This study aimed to deve...

Development and validation of a modified SOFA score for mortality prediction in candidemia patients.

Scientific reports
Candidemia is a life-threatening bloodstream infection associated with high mortality rates, particularly in critically ill patients. Accurate risk stratification is crucial for timely intervention and could improve patient outcomes. This study aimed...

A machine learning model for early candidemia prediction in the intensive care unit: Clinical application.

PloS one
Candidemia often poses a diagnostic challenge due to the lack of specific clinical features, and delayed antifungal therapy can significantly increase mortality rates, particularly in the intensive care unit (ICU). This study aims to develop a machin...

A privacy-preserving platform oriented medical healthcare and its application in identifying patients with candidemia.

Scientific reports
Federated learning (FL) has emerged as a significant method for developing machine learning models across multiple devices without centralized data collection. Candidemia, a critical but rare disease in ICUs, poses challenges in early detection and t...

Towards the automatic calculation of the EQUAL Candida Score: Extraction of CVC-related information from EMRs of critically ill patients with candidemia in Intensive Care Units.

Journal of biomedical informatics
OBJECTIVES: Candidemia is the most frequent invasive fungal disease and the fourth most frequent bloodstream infection in hospitalized patients. Its optimal management is crucial for improving patients' survival. The quality of candidemia management ...

Prediction of candidemia with machine learning techniques: state of the art.

Future microbiology
In this narrative review, we discuss studies assessing the use of machine learning (ML) models for the early diagnosis of candidemia, focusing on employed models and the related implications. There are currently few studies evaluating ML techniques f...

Personalized machine learning approach to predict candidemia in medical wards.

Infection
PURPOSE: Candidemia is a highly lethal infection; several scores have been developed to assist the diagnosis process and recently different models have been proposed. Aim of this work was to assess predictive performance of a Random Forest (RF) algor...

An integrated bioinformatics and machine learning-based approach to depict key immunological players associated with candidemia during immunodeficiency.

Computational biology and chemistry
It is evident that a robust immune system keeps Candida albicans infection in check, but weakened immunity opens the door for shifting from a benign yeast form to an invasive hyphal form which leads to systemic candidiasis with high mortality rate. H...