AIMC Topic: Cerebral Cortex

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Interpretable machine learning approach for neuron-centric analysis of human cortical cytoarchitecture.

Scientific reports
The complexity of the cerebral cortex underlies its function and distinguishes us as humans. Here, we present a principled veridical data science methodology for quantitative histology that shifts focus from image-level investigations towards neuron-...

Decoding reappraisal and suppression from neural circuits: A combined supervised and unsupervised machine learning approach.

Cognitive, affective & behavioral neuroscience
Emotion regulation is a core construct of mental health and deficits in emotion regulation abilities lead to psychological disorders. Reappraisal and suppression are two widely studied emotion regulation strategies but, possibly due to methodological...

Automatic detection of punctate white matter lesions in infants using deep learning of composite images from two cases.

Scientific reports
Punctate white matter lesions (PWMLs) in infants may be related to neurodevelopmental outcomes based on the location or number of lesions. This study aimed to assess the automatic detectability of PWMLs in infants on deep learning using composite ima...

iBEAT V2.0: a multisite-applicable, deep learning-based pipeline for infant cerebral cortical surface reconstruction.

Nature protocols
The human cerebral cortex undergoes dramatic and critical development during early postnatal stages. Benefiting from advances in neuroimaging, many infant brain magnetic resonance imaging (MRI) datasets have been collected from multiple imaging sites...

The identification of interacting brain networks during robot-assisted training with multimodal stimulation.

Journal of neural engineering
Robot-assisted rehabilitation training is an effective way to assist rehabilitation therapy. So far, various robotic devices have been developed for automatic training of central nervous system following injury. Multimodal stimulation such as visual ...

Machine learning sequence prioritization for cell type-specific enhancer design.

eLife
Recent discoveries of extreme cellular diversity in the brain warrant rapid development of technologies to access specific cell populations within heterogeneous tissue. Available approaches for engineering-targeted technologies for new neuron subtype...

Unsupervised learning of brain state dynamics during emotion imagination using high-density EEG.

NeuroImage
This study applies adaptive mixture independent component analysis (AMICA) to learn a set of ICA models, each optimized by fitting a distributional model for each identified component process while maximizing component process independence within som...

Sequential method for fast neural population activity reconstruction in the cortex from incomplete noisy measurements.

Computers in biology and medicine
During recent years there has been a growing interest in stochastic dynamic neural fields employed for modeling and predictions in biomedical and technical systems. In this paper, given some incomplete noisy data available from sensors, we propose an...

A dynamic graph convolutional neural network framework reveals new insights into connectome dysfunctions in ADHD.

NeuroImage
The pathological mechanism of attention deficit hyperactivity disorder (ADHD) is incompletely specified, which leads to difficulty in precise diagnosis. Functional magnetic resonance imaging (fMRI) has emerged as a common neuroimaging technique for s...

Unsupervised deep learning identifies semantic disentanglement in single inferotemporal face patch neurons.

Nature communications
In order to better understand how the brain perceives faces, it is important to know what objective drives learning in the ventral visual stream. To answer this question, we model neural responses to faces in the macaque inferotemporal (IT) cortex wi...