AIMC Topic: Coloring Agents

Clear Filters Showing 21 to 30 of 98 articles

Quantitative assessment of H&E staining for pathology: development and clinical evaluation of a novel system.

Diagnostic pathology
BACKGROUND: Staining tissue samples to visualise cellular detail and tissue structure is at the core of pathology diagnosis, but variations in staining can result in significantly different appearances of the tissue sample. While the human visual sys...

Application of machine learning-based read-across structure-property relationship (RASPR) as a new tool for predictive modelling: Prediction of power conversion efficiency (PCE) for selected classes of organic dyes in dye-sensitized solar cells (DSSCs).

Molecular informatics
The application of various in-silico-based approaches for the prediction of various properties of materials has been an effective alternative to experimental methods. Recently, the concepts of Quantitative structure-property relationship (QSPR) and r...

Bias reduction using combined stain normalization and augmentation for AI-based classification of histological images.

Computers in biology and medicine
Artificial intelligence (AI)-assisted diagnosis is an ongoing revolution in pathology. However, a frequent drawback of AI models is their propension to make decisions based rather on bias in training dataset than on concrete biological features, thus...

Combined colour deconvolution and artificial intelligence approach for region-selective immunohistochemical labelling quantification: The example of alpha smooth muscle actin in mouse kidney.

Journal of biophotonics
Immunohistochemical (IHC) localisation of protein expression is a widely used tool in pathology. This is semi-quantitative and exhibits substantial intra- and inter-observer variability. Digital approaches based on stain quantification applied to IHC...

Color-coded laparoscopic liver resection using artificial intelligence: A preliminary study.

Journal of hepato-biliary-pancreatic sciences
Tashiro and colleagues demonstrated for the first time that an artificial intelligence system can precisely identify intrahepatic vascular structures during laparoscopic liver resection in real time through color coding under bleeding and indocyanine...

Time for a full digital approach in nephropathology: a systematic review of current artificial intelligence applications and future directions.

Journal of nephrology
INTRODUCTION: Artificial intelligence (AI) integration in nephropathology has been growing rapidly in recent years, facing several challenges including the wide range of histological techniques used, the low occurrence of certain diseases, and the ne...

Deep learning-enabled realistic virtual histology with ultraviolet photoacoustic remote sensing microscopy.

Nature communications
The goal of oncologic surgeries is complete tumor resection, yet positive margins are frequently found postoperatively using gold standard H&E-stained histology methods. Frozen section analysis is sometimes performed for rapid intraoperative margin e...

COSMOS: a platform for real-time morphology-based, label-free cell sorting using deep learning.

Communications biology
Cells are the singular building blocks of life, and a comprehensive understanding of morphology, among other properties, is crucial to the assessment of underlying heterogeneity. We developed Computational Sorting and Mapping of Single Cells (COSMOS)...

Robot-assisted fluorescent sentinel lymph node identification in early-stage colon cancer.

Surgical endoscopy
BACKGROUND: Patients with cT1-2 colon cancer (CC) have a 10-20% risk of lymph node metastases. Sentinel lymph node identification (SLNi) could improve staging and reduce morbidity in future organ-preserving CC surgery. This pilot study aimed to asses...

Particle fusion of super-resolution data reveals the unit structure of Nup96 in Nuclear Pore Complex.

Scientific reports
Single molecule localization microscopy offers resolution nearly down to the molecular level with specific molecular labelling, and is thereby a promising tool for structural biology. In practice, however, the actual value to this field is limited pr...