AIMC Topic: Computer Simulation

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The Impact of Undersampling on the Predictive Performance of Logistic Regression and Machine Learning Algorithms: A Simulation Study.

Epidemiology (Cambridge, Mass.) Sep 1, 2020
Algorithms Computer Simulation Humans Logistic Models Selection Bias Machine Learning
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Revealing new therapeutic opportunities through drug target prediction: a class imbalance-tolerant machine learning approach.

Bioinformatics (Oxford, England) Aug 15, 2020
MOTIVATION: In silico drug target prediction provides valuable information for drug repurposing, understanding of side effects as well as expansion of the druggable genome. In particular, discovery of actionable drug targets is critical to developing...
Machine Learning Computer Simulation Computational Biology Drug Repositioning
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DeepCLIP: predicting the effect of mutations on protein-RNA binding with deep learning.

Nucleic acids research Jul 27, 2020
Nucleotide variants can cause functional changes by altering protein-RNA binding in various ways that are not easy to predict. This can affect processes such as splicing, nuclear shuttling, and stability of the transcript. Therefore, correct modeling...
RNA Base Sequence Nucleic Acid Conformation Computational Biology RNA-Binding Proteins Mutation Binding Sites Nucleotide Motifs Humans Computer Simulation Animals Deep Learning Protein Binding Mice
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Designing an optimal inventory management model for the blood supply chain: Synthesis of reusable simulation and neural network.

Medicine Jul 17, 2020
Blood supply managers in the blood supply chain have always sought to create enough reserves to increase access to different blood products and reduce the mortality rate resulting from expired blood. Managers' adequate and timely response to their cu...
Humans Neural Networks, Computer Computer Simulation Blood Transfusion Inventories, Hospital Models, Statistical Iran Blood Banks
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mRNALoc: a novel machine-learning based in-silico tool to predict mRNA subcellular localization.

Nucleic acids research Jul 2, 2020
Recent evidences suggest that the localization of mRNAs near the subcellular compartment of the translated proteins is a more robust cellular tool, which optimizes protein expression, post-transcriptionally. Retention of mRNA in the nucleus can regul...
Software Computer Simulation RNA, Messenger Sequence Analysis, RNA Support Vector Machine Cell Nucleus Mitochondria Cytoplasm Endoplasmic Reticulum
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Generating sequential electronic health records using dual adversarial autoencoder.

Journal of the American Medical Informatics Association : JAMIA Jul 1, 2020
OBJECTIVE: Recent studies on electronic health records (EHRs) started to learn deep generative models and synthesize a huge amount of realistic records, in order to address significant privacy issues surrounding the EHR. However, most of them only fo...
Electronic Health Records Confidentiality Machine Learning Software Humans Computer Simulation Neural Networks, Computer
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Using Machine Learning to Estimate Unobserved COVID-19 Infections in North America.

The Journal of bone and joint surgery. American volume Jul 1, 2020
BACKGROUND: The detection of coronavirus disease 2019 (COVID-19) cases remains a huge challenge. As of April 22, 2020, the COVID-19 pandemic continues to take its toll, with >2.6 million confirmed infections and >183,000 deaths. Dire projections are ...
North America Betacoronavirus Pneumonia, Viral United States Pandemics Humans Bayes Theorem COVID-19 Coronavirus Infections Computer Simulation Machine Learning Forecasting SARS-CoV-2 Canada
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Dr. Agent: Clinical predictive model via mimicked second opinions.

Journal of the American Medical Informatics Association : JAMIA Jul 1, 2020
OBJECTIVE: Prediction of disease phenotypes and their outcomes is a difficult task. In practice, patients routinely seek second opinions from multiple clinical experts for complex disease diagnosis. Our objective is to mimic such a practice of seekin...
Neural Networks, Computer Computer Simulation Prognosis Humans Hospital Mortality Disease Progression Logistic Models Deep Learning Referral and Consultation Length of Stay
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[Application of convolutional neural network to risk evaluation of positive circumferential resection margin of rectal cancer by magnetic resonance imaging].

Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery Jun 25, 2020
To explore the feasibility of using faster regional convolutional neural network (Faster R-CNN) to evaluate the status of circumferential resection margin (CRM) of rectal cancer in the magnetic resonance imaging (MRI). This study was registered in ...
Margins of Excision Humans Neural Networks, Computer Computer Simulation Feasibility Studies Risk Assessment Models, Biological Neoadjuvant Therapy Rectal Neoplasms Magnetic Resonance Imaging
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Field performance of sterile male mosquitoes released from an uncrewed aerial vehicle.

Science robotics Jun 15, 2020
Genetic control methods of mosquito vectors of malaria, dengue, yellow fever, and Zika are becoming increasingly popular due to the limitations of other techniques such as the use of insecticides. The sterile insect technique is an effective genetic ...
Mosquito Control Mosquito Vectors Vector Borne Diseases Brazil Robotics Female Equipment Design Humans Infertility, Male Animals Software Aircraft Male Computer Simulation Aedes
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