AIMC Topic: Computers, Molecular
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DNA Molecular Computing with Weighted Signal Amplification for Cancer miRNA Biomarker Diagnostics.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Apr 11, 2025
The expression levels of microRNAs (miRNAs) are strongly linked to cancer progression, making them promising biomarkers for cancer detection. Enzyme-free signal amplification DNA circuits have facilitated the detection of low-abundance miRNAs. Howeve...
Neural Network With Attention Mechanism for Abnormality Detection and Localization in Diffusive Molecular Communication.
IEEE transactions on nanobioscience
Mar 26, 2025
Diffusive molecular communication (DMC) is an emerging paradigm in nanotechnology, which provides biocompatibility and nanoscale communication for many promising applications, such as targeted drug delivery, environmental monitoring, etc. However, de...
Rewireable Building Blocks for Enzyme-Powered DNA Computing Networks.
Journal of the American Chemical Society
Sep 10, 2024
Neural networks enable the processing of large, complex data sets with applications in disease diagnosis, cell profiling, and drug discovery. Beyond electronic computers, neural networks have been implemented using programmable biomolecules such as D...
A novel activation function based on DNA enzyme-free hybridization reaction and its implementation on nonlinear molecular learning systems.
Physical chemistry chemical physics : PCCP
Apr 17, 2024
With the advent of the post-Moore's Law era, the development of traditional silicon-based computers has reached its limit, and there is an urgent need to develop new computing technologies to meet the needs of science, technology, and daily life. Due...
Molecular Computation for Molecular Classification.
Advanced biology
Jan 29, 2023
DNA as an informational polymer has, for the past 30 years, progressively become an essential molecule to rationally build chemical reaction networks endowed with powerful signal-processing capabilities. Whether influenced by the silicon world or ins...
Nonlinear decision-making with enzymatic neural networks.
Nature
Oct 19, 2022
Artificial neural networks have revolutionized electronic computing. Similarly, molecular networks with neuromorphic architectures may enable molecular decision-making on a level comparable to gene regulatory networks. Non-enzymatic networks could in...
An RNA-based theory of natural universal computation.
Journal of theoretical biology
Dec 31, 2021
Life is confronted with computation problems in a variety of domains including animal behavior, single-cell behavior, and embryonic development. Yet we currently do not know of a naturally existing biological system that is capable of universal compu...
Scaling up DNA digital data storage by efficiently predicting DNA hybridisation using deep learning.
Scientific reports
Oct 15, 2021
Deoxyribonucleic acid (DNA) has shown great promise in enabling computational applications, most notably in the fields of DNA digital data storage and DNA computing. Information is encoded as DNA strands, which will naturally bind in solution, thus e...
Molecular and DNA Artificial Neural Networks via Fractional Coding.
IEEE transactions on biomedical circuits and systems
Mar 9, 2020
This article considers implementation of artificial neural networks (ANNs) using molecular computing and DNA based on fractional coding. Prior work had addressed molecular two-layer ANNs with binary inputs and arbitrary weights. In prior work using f...
A novel bio-heuristic computing algorithm to solve the capacitated vehicle routing problem based on Adleman-Lipton model.
Bio Systems
Jul 29, 2019
DNA computing, as one of potential means to solve complicated computational problems, is a new field of interdisciplinary research, including computational mathematics, parallel algorithms, bioinformatics. Capacitated vehicle routing problem is one o...
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