AIMC Topic: Nucleic Acid Hybridization
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Hybridization of the swarming and interior point algorithms to solve the Rabinovich-Fabrikant system.
Scientific reports
Jul 6, 2023
In this study, a trustworthy swarming computing procedure is demonstrated for solving the nonlinear dynamics of the Rabinovich-Fabrikant system. The nonlinear system's dynamic depends upon the three differential equations. The computational stochasti...
Scaling up DNA digital data storage by efficiently predicting DNA hybridisation using deep learning.
Scientific reports
Oct 15, 2021
Deoxyribonucleic acid (DNA) has shown great promise in enabling computational applications, most notably in the fields of DNA digital data storage and DNA computing. Information is encoded as DNA strands, which will naturally bind in solution, thus e...
Homogeneous DNA-only keypad locks enable one-pot assay of multi-inputs.
Chemical communications (Cambridge, England)
Jun 3, 2020
Homogeneous DNA-only keypad locks were built with multi-stranded scalable junction substrates and a series of double-stranded eliminators to differentially process correctly- and wrongly-added DNA inputs, respectively. Unlike conventional strategies ...
A tri-functional probe mediated exponential amplification strategy for highly sensitive detection of Dnmt1 and UDG activities at single-cell level.
Analytica chimica acta
Dec 23, 2019
Multiplex DNA methylation and glycosylation are ubiquitous in the human body to ensure the normal function and stability of the genome. The methyltransferases and glycosylases rely on varied enzymes with different action mechanism, which still remain...
Highly sensitive electrochemical biosensor for streptavidin detection based on CdSe quantum dots.
Biosensors & bioelectronics
Dec 18, 2017
An electrochemical biosensor was developed based on a steric hindrance hybridization assay to allow the highly sensitive detection of streptavidin. In the steric hindrance hybridization assay, the signaling strand DNA (sig-DNA) was labeled at the 3' ...
Development of amino functionalized carbon coated magnetic nanoparticles and their application to electrochemical detection of hybridization of nucleic acids.
Talanta
Nov 11, 2016
In our study, the development of amino functionalized carbon coated magnetic nanoparticles (NH-CC-MNPs) and their usage for electrochemical detection of hybridization of nucleic acids have been aimed. Firstly, NH-CC-MNPs were prepared by coating of p...
A Novel Linear Machine Learning Method Based on DNA Hybridization Reaction Circuit.
IEEE transactions on nanobioscience
Jul 1, 2025
DNA hybridization reaction is a significant technology in the field of semi-synthetic biology and holds great potential for use in biological computation. In this study, we propose a novel machine learning model based on a DNA hybridization reaction ...
Deqformer: high-definition and scalable deep learning probe design method.
Briefings in bioinformatics
Jan 22, 2024
Target enrichment sequencing techniques are gaining widespread use in the field of genomics, prized for their economic efficiency and swift processing times. However, their success depends on the performance of probes and the evenness of sequencing d...
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