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Coronary Artery Disease

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Deep learning-based prediction of coronary artery stenosis resistance.

American journal of physiology. Heart and circulatory physiology
Coronary artery stenosis resistance (SR) is a key factor for noninvasive calculations of fractional flow reserve derived from coronary CT angiography (FFR). Existing computational fluid dynamics (CFD) methods, including three-dimensional (3-D) comput...

Direct Risk Assessment From Myocardial Perfusion Imaging Using Explainable Deep Learning.

JACC. Cardiovascular imaging
BACKGROUND: Myocardial perfusion imaging (MPI) is frequently used to provide risk stratification, but methods to improve the accuracy of these predictions are needed.

Deep Learning Coronary Artery Calcium Scores from SPECT/CT Attenuation Maps Improve Prediction of Major Adverse Cardiac Events.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Low-dose ungated CT attenuation correction (CTAC) scans are commonly obtained with SPECT/CT myocardial perfusion imaging. Despite the characteristically low image quality of CTAC, deep learning (DL) can potentially quantify coronary artery calcium (C...

Mitigating bias in deep learning for diagnosis of coronary artery disease from myocardial perfusion SPECT images.

European journal of nuclear medicine and molecular imaging
PURPOSE: Artificial intelligence (AI) has high diagnostic accuracy for coronary artery disease (CAD) from myocardial perfusion imaging (MPI). However, when trained using high-risk populations (such as patients with correlating invasive testing), the ...

Deep Learning-Based Attenuation Correction Improves Diagnostic Accuracy of Cardiac SPECT.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
To improve diagnostic accuracy, myocardial perfusion imaging (MPI) SPECT studies can use CT-based attenuation correction (AC). However, CT-based AC is not available for most SPECT systems in clinical use, increases radiation exposure, and is impacted...

Deep Learning for Explainable Estimation of Mortality Risk From Myocardial Positron Emission Tomography Images.

Circulation. Cardiovascular imaging
BACKGROUND: We aim to develop an explainable deep learning (DL) network for the prediction of all-cause mortality directly from positron emission tomography myocardial perfusion imaging flow and perfusion polar map data and evaluate it using prospect...

Deep Learning of Coronary Calcium Scores From PET/CT Attenuation Maps Accurately Predicts Adverse Cardiovascular Events.

JACC. Cardiovascular imaging
BACKGROUND: Assessment of coronary artery calcium (CAC) by computed tomographic (CT) imaging provides an accurate measure of atherosclerotic burden. CAC is also visible in computed tomographic attenuation correction (CTAC) scans, always acquired with...

Polar map-free 3D deep learning algorithm to predict obstructive coronary artery disease with myocardial perfusion CZT-SPECT.

European journal of nuclear medicine and molecular imaging
PURPOSE: Deep learning (DL) models have been shown to outperform total perfusion deficit (TPD) quantification in predicting obstructive coronary artery disease (CAD) from myocardial perfusion imaging (MPI). However, previously published methods have ...

Deep learning artificial intelligence framework for multiclass coronary artery disease prediction using combination of conventional risk factors, carotid ultrasound, and intraplaque neovascularization.

Computers in biology and medicine
OBJECTIVE: Cardiovascular disease (CVD) is a major healthcare challenge and therefore early risk assessment is vital. Previous assessment techniques use either "conventional CVD risk calculators (CCVRC)" or machine learning (ML) paradigms. These tech...