International journal of data mining and bioinformatics
Jan 1, 2015
Gene function prediction is an important problem in bioinformatics. Due to the inherent noise existing in the gene expression data, the attempt to improve the prediction accuracy resorting to new classification techniques is limited. With the emergen...
International journal of data mining and bioinformatics
Jan 1, 2015
The text mining methods proposed to discover associations between pairs of biological entities by mining a scientific literature often extract associations already existing in the literature, whereas their extensions supervise too much the discovery ...
International journal of data mining and bioinformatics
Jan 1, 2015
Biological data are often high in dimension while the number of samples is small. In such cases, the performance of classification can be improved by reducing the dimension of data, which is referred to as feature selection. Recently, a novel feature...
International journal of data mining and bioinformatics
Jan 1, 2015
Real-Time Quantitative Polymerase Chain Reaction (qRT-PCR) is widely used in biological research. It is a key to the availability of qRT-PCR experiment to select a stable reference gene. However, selecting an appropriate reference gene usually requir...
Technology and health care : official journal of the European Society for Engineering and Medicine
Jan 1, 2015
BACKGROUND: To collect medical datasets, it is usually the case that a number of data samples contain some missing values. Performing the data mining task over the incomplete datasets is a difficult problem. In general, missing value imputation can b...
Technology and health care : official journal of the European Society for Engineering and Medicine
Jan 1, 2015
BACKGROUND: Bronchitis is considered a non-specific inflammation in the peripheral tissues of the trachea and bronchus. Many therapeutic schemes for chronic bronchitis have been reported in existing research.
To address the imbalanced classification problem emerging in Bioinformatics, a boundary movement-based extreme learning machine (ELM) algorithm called BM-ELM was proposed. BM-ELM tries to firstly explore the prior information about data distribution ...
G-protein-coupled receptors (GPCRs) are seven membrane-spanning proteins and regulate many important physiological processes, such as vision, neurotransmission, immune response and so on. GPCRs-related pathways are the targets of a large number of ma...
In this paper, we introduce a new powerful scientific paradigm to understand natural and cultural processes. This new paradigm is based on two fundamental keywords: Data, as representative sample of the process we need to analyze, and Artificial Adap...
IEEE/ACM transactions on computational biology and bioinformatics
Jan 1, 2015
A major challenge in computational biology is to find simple representations of high-dimensional data that best reveal the underlying structure. In this work, we present an intuitive and easy-to-implement method based on ranked neighborhood compariso...
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