IEEE/ACM transactions on computational biology and bioinformatics
Feb 3, 2023
A DNA motif is a sequence pattern shared by the DNA sequence segments that bind to a specific protein. Discovering motifs in a given DNA sequence dataset plays a vital role in studying gene expression regulation. As an important attribute of the DNA ...
IEEE/ACM transactions on computational biology and bioinformatics
Feb 3, 2023
Identifying enhancers is a critical task in bioinformatics due to their primary role in regulating gene expression. For this reason, various computational algorithms devoted to enhancer identification have been put forward over the years. More featur...
IEEE/ACM transactions on computational biology and bioinformatics
Feb 3, 2023
Analyzing mass spectrometry-based proteomics data with deep learning (DL) approaches poses several challenges due to the high dimensionality, low sample size, and high level of noise. Additionally, DL-based workflows are often hindered to be integrat...
IEEE/ACM transactions on computational biology and bioinformatics
Feb 3, 2023
Drug failures due to unforeseen adverse effects at clinical trials pose health risks for the participants and lead to substantial financial losses. Side effect prediction algorithms have the potential to guide the drug design process. LINCS L1000 dat...
IEEE/ACM transactions on computational biology and bioinformatics
Feb 3, 2023
Identification of DNA-binding proteins (DBPs) and RNA-binding proteins (RBPs) from the primary sequences is essential for further exploring protein-nucleic acid interactions. Previous studies have shown that machine-learning-based methods can efficie...
The Journal of thoracic and cardiovascular surgery
Feb 2, 2023
OBJECTIVES: The aim of this study using decision curve analysis (DCA) was to evaluate the clinical utility of a deep-learning mortality prediction model for cardiac surgery decision making compared with the European System for Cardiac Operative Risk ...
Journal of magnetic resonance imaging : JMRI
Feb 2, 2023
BACKGROUND: Although susceptibility-weighted imaging (SWI) is the gold standard for visualizing cerebral microbleeds (CMBs) in the brain, the required phase data are not always available clinically. Having a postprocessing tool for generating SWI con...
Clinical chemistry and laboratory medicine
Feb 2, 2023
OBJECTIVES: VEXAS syndrome is a newly described autoinflammatory disease associated with somatic mutations and vacuolization of myeloid precursors. This disease possesses an increasingly broad spectrum, leading to an increase in the number of suspec...
International journal of legal medicine
Feb 2, 2023
BACKGROUND: Deep learning is a promising technique to improve radiological age assessment. However, expensive manual annotation by experts poses a bottleneck for creating large datasets to appropriately train deep neural networks. We propose an objec...
Computer methods and programs in biomedicine
Feb 2, 2023
BACKGROUND AND OBJECTIVE: Current studies based on digital biopsy images have achieved satisfactory results in detecting colon cancer despite their limited visual spectral range. Such methods may be less accurate when applied to samples taken from th...
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