In the recent COVID-19 pandemic, SARS-CoV-2 infection spread worldwide. The 3C-like protease (3CLpro) is a promising drug target for SARS-CoV-2. We constructed a deep learning-based convolutional neural network-quantitative structure-activity relat...
OBJECTIVE: Accurate segmentation of liver tumors, which could help physicians make appropriate treatment decisions and assess the effectiveness of surgical treatment, is crucial for the clinical diagnosis of liver cancer. In this study, we propose a ...
Limited angle reconstruction is a typical ill-posed problem in computed tomography (CT). Given incomplete projection data, images reconstructed by conventional analytical algorithms and iterative methods suffer from severe structural distortions and ...
Magnetoencephalography (MEG) is a useful tool for clinically evaluating the localization of interictal spikes. Neurophysiologists visually identify spikes from the MEG waveforms and estimate the equivalent current dipoles (ECD). However, presently, t...
Laser osteotomy promises precise cutting and minor bone tissue damage. We proposed Optical Coherence Tomography (OCT) to monitor the ablation process toward our smart laser osteotomy approach. The OCT image is helpful to identify tissue type and prov...
Percutaneous coronary intervention is widely applied for the treatment of coronary artery disease under the guidance of X-ray coronary angiography (XCA) image. However, the projective nature of XCA causes the loss of 3D structural information, which ...
Cancer prognosis analysis is of essential interest in clinical practice. In order to explore the prognostic power of computational histopathology and genomics, this paper constructs a multi-modality prognostic model for survival prediction. We collec...
Over a billion people around the world are disabled, among whom 253 million are visually impaired or blind, and this number is greatly increasing due to ageing, chronic diseases, and poor environments and health. Despite many proposals, the current d...
. Neuroimaging uncovers important information about disease in the brain. Yet in Alzheimer's disease (AD), there remains a clear clinical need for reliable tools to extract diagnoses from neuroimages. Significant work has been done to develop deep le...
Over the years, with the widespread use of computer technology and the dramatic increase in electronic medical data, data-driven approaches to medical data analysis have emerged. However, the analysis of medical data remains challenging due to the mi...
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