We present a deep learning approach to obtain high-resolution (HR) fluorescence lifetime images from low-resolution (LR) images acquired from fluorescence lifetime imaging (FLIM) systems. We first proposed a theoretical method for training neural net...
MOTIVATION: Protein model quality assessment is a key component of protein structure prediction. In recent research, the voxelization feature was used to characterize the local structural information of residues, but it may be insufficient for descri...
MOTIVATION: Accurately predicting protein secondary structure and relative solvent accessibility is important for the study of protein evolution, structure and an early-stage component of typical protein 3D structure prediction pipelines.
MOTIVATION: Mass spectrometry imaging (MSI) provides rich biochemical information in a label-free manner and therefore holds promise to substantially impact current practice in disease diagnosis. However, the complex nature of MSI data poses computat...
Mathematical biosciences and engineering : MBE
Mar 16, 2022
The outbreak of the Corona Virus Disease 2019 (COVID-19) has posed a serious threat to human health and life around the world. As the number of COVID-19 cases continues to increase, many countries are facing problems such as errors in nucleic acid te...
Frontiers in bioscience (Landmark edition)
Mar 16, 2022
BACKGROUND: Dynamic contrast-enhanced (DCE) MRI is widely used to assess vascular perfusion and permeability in cancer. In small animal applications, conventional modeling of pharmacokinetic (PK) parameters from DCE MRI images is complex and time con...
We report on the potential to perform image reconstruction in 3D k-space reflectance fluorescence tomography (FT) using deep learning (DL). Herein, we adopt a modified AUTOMAP architecture and develop a training methodology that leverages an open-sou...
We present an open-source eigenmode expansion (EME) software package entirely implemented in the Python programming language. Eigenmode expansion Python (EMEPy) utilizes artificial neural networks to reproduce electromagnetic eigenmode field profiles...
A Mueller matrix (MM) provides a comprehensive representation of the polarization properties of a complex medium and encodes very rich information on the macro- and microstructural features. Histopathological features can be characterized by polariza...
N6-methyladenine (6mA) is associated with important roles in DNA replication, DNA repair, transcription, regulation of gene expression. Several experimental methods were used to identify DNA modifications. However, these experimental methods are cost...
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