Journal of chemical information and modeling
Jul 9, 2025
In recent years, generative deep learning has emerged as a transformative approach in drug design, promising to explore the vast chemical space and generate novel molecules with desired biological properties. This perspective examines the challenges ...
INTRODUCTION: Brucella spondylitis (BS) and tuberculous spondylitis (TS) are prevalent spinal infections with distinct treatment protocols. Rapid and accurate differentiation between these two conditions is crucial for effective clinical management; ...
BACKGROUND: Myopia is a major cause of vision impairment. To improve the efficiency of myopia screening, this paper proposes a deep learning model, X-ENet, which combines the advantages of depthwise separable convolution and dynamic convolution to cl...
Tonsilloliths can be seen on panoramic radiographs (PRs) as deposits located on the middle portion of the ramus of the mandible. Although tonsilloliths are clinically harmless, the high risk of misdiagnosis leads to unnecessary advanced examinations ...
Dissolved oxygen (DO) is a vital parameter in regulating water quality and sustaining the health of aquatic organisms in aquaculture environments. Therefore, estimation and control of DO levels are essential in aquaculture operations. However, tradit...
Diabetic retinopathy (DR) is an age-related macular degeneration eye disease problem that causes pathological changes in the retinal neural and vascular system. Recently, fundus imaging is a popular technology and widely used for clinical diagnosis, ...
Magnetic resonance imaging of the lumbar spine is a key technique for clarifying the cause of disease. The greatest challenges today are the repetitive and time-consuming process of interpreting these complex MR images and the problem of unequal diag...
Monkeypox (Mpox), caused by the monkeypox virus, has become a global concern due to its rising cases and resemblance to other rash-causing diseases like chickenpox and measles. Traditional diagnostic methods, including visual examination and PCR test...
The efficiency of the swarm-based approach depends on the perfect balance of operators: exploration and exploitation. Due to a lack of balance between these two factors, the Salp Swarm Algorithm (SSA), a recently developed swarm-based metaheuristic a...
The progression of Alzheimer's disease is relentless, leading to a worsening of mental faculties over time. Currently, there is no remedy for this illness. Accurate detection and prompt intervention are pivotal in mitigating the progression of the di...
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