AI Medical Compendium Topic

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Dictyostelium

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Democratized image analytics by visual programming through integration of deep models and small-scale machine learning.

Nature communications
Analysis of biomedical images requires computational expertize that are uncommon among biomedical scientists. Deep learning approaches for image analysis provide an opportunity to develop user-friendly tools for exploratory data analysis. Here, we us...

A swarm design paradigm unifying swarm behaviors using minimalistic communication.

Bioinspiration & biomimetics
Numerous nature inspired algorithms have been suggested to enable robotic swarms, mobile sensor networks and other multi-agent systems to exhibit various self-organized behaviors. Swarm intelligence and swarm robotics research have been underway for ...

The Gene Ontology resource: enriching a GOld mine.

Nucleic acids research
The Gene Ontology Consortium (GOC) provides the most comprehensive resource currently available for computable knowledge regarding the functions of genes and gene products. Here, we report the advances of the consortium over the past two years. The n...

A Curvature-Enhanced Random Walker Segmentation Method for Detailed Capture of 3D Cell Surface Membranes.

IEEE transactions on medical imaging
High-resolution 3D microscopy is a fast advancing field and requires new techniques in image analysis to handle these new datasets. In this work, we focus on detailed 3D segmentation of Dictyostelium cells undergoing macropinocytosis captured on an i...

Comparative mapping of crawling-cell morphodynamics in deep learning-based feature space.

PLoS computational biology
Navigation of fast migrating cells such as amoeba Dictyostelium and immune cells are tightly associated with their morphologies that range from steady polarized forms that support high directionality to those more complex and variable when making fre...

Forecasting and Predicting Stochastic Agent-Based Model Data with Biologically-Informed Neural Networks.

Bulletin of mathematical biology
Collective migration is an important component of many biological processes, including wound healing, tumorigenesis, and embryo development. Spatial agent-based models (ABMs) are often used to model collective migration, but it is challenging to thor...

Spatiotemporal feature learning for actin dynamics.

PloS one
The social amoeba Dictyostelium discoideum is a standard model system for studying cell motility and formation of biological patterns. D. discoideum cells form protrusions and migrate via cytoskeletal reorganization driven by coordinated waves of act...